Spinal muscular atrophy is an autosomal recessive neurodegenerative disease
characterised by degeneration of spinal cord motor neurons, atrophy of skeletal muscles …

Stem cell–based approaches have received much hype as potential treatments for
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

Many common neurological disorders, such as Parkinson's disease, stroke and multiple
sclerosis, are caused by a loss of neurons and glial cells. In recent years, neurons and glia …

Recent progress shows that neurons suitable for transplantation can be generated from
stem cells in culture, and that the adult brain produces new neurons from its own stem cells …

Stem cells represent natural units of embryonic development and tissue regeneration.
Embryonic stem (ES) cells, in particular, possess a nearly unlimited self-renewal capacity …

Human neurological disorders such as Parkinson's disease, Huntington's disease,
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …

Cellular abnormalities in amyotrophic lateral sclerosis (ALS) are not limited to motor
neurons. Astrocyte dysfunction also occurs in human ALS and transgenic rodents …

Spinal muscular atrophy (SMA) is a neurodegenerative disease in humans and the most
common genetic cause of infant mortality. The disease results in motor neuron loss and …

Human neurodegenrative diseases such as P arkinson's disease (PD), H untington's
disease (HD), amyotrophic lateral sclerosis (ALS) and A lzheimer's disease (AD) are caused …