Candida albicans cell-type switching and functional plasticity in the mammalian host
SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
Molecular evolution of antifungal drug resistance
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
Growth of Candida albicans hyphae
PE Sudbery - Nature Reviews Microbiology, 2011 - nature.com
The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Morphological and Metabolic Engineering of Yarrowia lipolytica to Increase β-Carotene Production
M Liu, J Zhang, J Ye, Q Qi, J Hou - ACS Synthetic Biology, 2021 - ACS Publications
The oleaginous yeast Yarrowia lipolytica represents an environmentally friendly platform cell
factory for β-carotene production. However, Y. lipolytica is a dimorphic species that can …
factory for β-carotene production. However, Y. lipolytica is a dimorphic species that can …
Fungal dimorphism: the switch from hyphae to yeast is a specialized morphogenetic adaptation allowing colonization of a host
KJ Boyce, A Andrianopoulos - FEMS microbiology reviews, 2015 - academic.oup.com
The ability of pathogenic fungi to switch between a multicellular hyphal and unicellular yeast
growth form is a tightly regulated process known as dimorphic switching. Dimorphic …
growth form is a tightly regulated process known as dimorphic switching. Dimorphic …
Morphogenesis in Candida albicans
M Whiteway, C Bachewich - Annu. Rev. Microbiol., 2007 - annualreviews.org
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form
or a hyphal form. The switch between these forms is the result of a complex interplay of …
or a hyphal form. The switch between these forms is the result of a complex interplay of …
Candida albicans: A Model Organism for Studying Fungal Pathogens
Candida albicans is an opportunistic human fungal pathogen that causes candidiasis. As
healthcare has been improved worldwide, the number of immunocompromised patients has …
healthcare has been improved worldwide, the number of immunocompromised patients has …
Mitogen-activated protein kinase pathways and fungal pathogenesis
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …
[PDF][PDF] Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence
T Klengel, WJ Liang, J Chaloupka, C Ruoff… - Current Biology, 2005 - cell.com
The ascomycete Candida albicans is the most common fungal pathogen in
immunocompromised patients [1]. Its ability to change morphology, from yeast to filamentous …
immunocompromised patients [1]. Its ability to change morphology, from yeast to filamentous …