Introduction: There is a major epidemic of obesity, and many obese patients suffer with
respiratory symptoms and disease. The overall impact of obesity on lung function is …

Information for Category 1 CME Credit Credit can now be obtained, free for a limited time, by
reading the review articles in this issue. Please note the following instructions. Method of …

This review focuses on one family of the known cAMP receptors, the exchange proteins
directly activated by cAMP (EPACs), also known as the cAMP-regulated guanine nucleotide …

A link between metabolic syndrome (MetS) and lung diseases has been observed in several
cross-sectional and longitudinal studies. This syndrome has been identified as an …

It is now established that airway smooth muscle (ASM) has roles in determining airway
structure and function, well beyond that as the major contractile element. Indeed, changes in …

Background Obesity increases both the risk of asthma and asthma severity and is a well-
known risk factor for insulin resistance and the metabolic syndrome (MS) in children and …

BACKGROUND: Diabetes mellitus is a systemic disorder associated with inflammation and
oxidative stress which may target many organs such as the kidney, retina, and the vascular …

Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an
important factor in separating the phenotypes. Most studies with asthma have been …

Chronic asthma is an inflammatory airways disease characterized by pathological changes
in the airway smooth muscle (ASM) bundle that contribute to airway obstruction and …

The effect of obesity, weight gain, and weight loss on asthm... : Current Opinion in Allergy and
Clinical Immunology The effect of obesity, weight gain, and weight loss on asthma inception …