[HTML][HTML] Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

MA Feitelson, A Arzumanyan, RJ Kulathinal… - Seminars in cancer …, 2015 - Elsevier
Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

[HTML][HTML] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

S Prasad, AK Tyagi… - Cancer research and …, 2014 - synapse.koreamed.org
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral …

[HTML][HTML] Renoprotective effect of the antioxidant curcumin: Recent findings

J Trujillo, YI Chirino, E Molina-Jijón… - Redox biology, 2013 - Elsevier
For years, there have been studies based on the use of natural compounds plant-derived as
potential therapeutic agents for various diseases in humans. Curcumin is a phenolic …

Curcumin: the Indian solid gold

BB Aggarwal, C Sundaram, N Malani… - The molecular targets and …, 2007 - Springer
Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

Induction of oxidative stress in kidney

E Ozbek - International journal of nephrology, 2012 - Wiley Online Library
Oxidative stress has a critical role in the pathophysiology of several kidney diseases, and
many complications of these diseases are mediated by oxidative stress, oxidative stress …

Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs

A Goel, BB Aggarwal - Nutrition and cancer, 2010 - Taylor & Francis
Curcumin (diferuloylmethane), the yellow pigment in Indian saffron (Curcuma longa; also
called turmeric, haldi, or haridara in the East and curry powder in the West), has been …

Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications

C Guo, G Dong, X Liang, Z Dong - Nature Reviews Nephrology, 2019 - nature.com
Acute kidney injury (AKI) is a major public health concern associated with high morbidity and
mortality. Despite decades of research, the pathogenesis of AKI remains incompletely …

Antioxidant potential of spices and their active constituents

K Srinivasan - Critical reviews in food science and nutrition, 2014 - Taylor & Francis
Excessive free radical generation overbalancing the rate of their removal leads to oxidative
stress. Oxidative stress has been implicated in the etiology of cardiovascular disease …

Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent

M López‐Lázaro - Molecular nutrition & food research, 2008 - Wiley Online Library
A growing body of research suggests that curcumin, the major active constituent of the
dietary spice turmeric, has potential for the prevention and therapy of cancer. Preclinical …

Curcumin nanoformulation for cervical cancer treatment

MS Zaman, N Chauhan, MM Yallapu, RK Gara… - Scientific reports, 2016 - nature.com
Cervical cancer is one of the most common cancers among women worldwide. Current
standards of care for cervical cancer includes surgery, radiation and chemotherapy …