Photocatalytic Carbosulfonylation/Cyclization of N-Homoallyl and N-Allyl Aldehyde Hydrazones toward Sulfonylated Tetrahydropyridazines and Dihydropyrazoles

Y Wu, X Wu, L Liu, JT Yu, C Pan - Organic Letters, 2023 - ACS Publications
N′-Benzylidene-N-homoallylacetohydrazides were designed and synthesized as novel
skeletons for the construction of functionalized tetrahydropyridazines. A series of aryl-and …

Synthesis of functionalized tetrahydropyridazines from hydrazones

S Yu, JT Yu, C Pan - Organic & Biomolecular Chemistry, 2024 - pubs.rsc.org
The tetrahydropyridazines motif widely presents in a plenty of natural products and
biologically active molecules. Easily prepared from the condensation of carbonyls with …

Chalcone-Based Synthesis of Tetrahydropyridazines via Cloke–Wilson-Type Rearrangement-Involved Tandem Reaction between Cyclopropyl Ketones and …

Y Meng, J Gu, M Xin, Y Jiang, Z Du, G Lu… - The Journal of …, 2024 - ACS Publications
A facile and efficient approach for the synthesis of multisubstituted tetrahydropyridazines
starting from cyclopropyl ketones and hydrazines has been developed. The transformation is …

Organocatalytic Enantioselective (4+ 2) Annulation of Cyclopropane Carbaldehydes with 2‐Mercapto‐1‐Arylethanones

N Yadav, A Hazra, P Singh… - Advanced Synthesis & …, 2024 - Wiley Online Library
Here, we report the organocatalytic enantioselective synthesis of dihydrothiopyran
derivatives from trans racemic donor–acceptor cyclopropane carbaldehydes (DACCs) and 2 …

Donor–Acceptor Cyclopropane Ring Expansion to 1, 2-Dihydronaphthalenes. Access to Bridged Seven-Membered Lactones

VV Shorokhov, SS Zhokhov, VB Rybakov… - Organic …, 2023 - ACS Publications
A Lewis-acid-promoted domino ring-opening cyclization of readily available donor–acceptor
cyclopropanes with a preinstalled electrophilic center, embedded in a donor group, to …

Converting Strain Release into Aromaticity Loss for Activation of Donor–Acceptor Cyclopropanes: Generation of Quinone Methide Traps for C-Nucleophiles

VV Shorokhov, BK Chabuka, TP Tikhonov… - Organic …, 2024 - ACS Publications
Here, we present a new approach for the activation of donor–acceptor cyclopropanes in ring-
opening reactions, which does not require the use of a Lewis or Brønsted acid as a catalyst …

Synthesis of Bridged Bicyclic Systems peri‐Annulated to the Indole Ring: Tropane‐Fused Indoles

SM Antropov, SA Tokmacheva, II Levina… - Advanced Synthesis …, 2024 - Wiley Online Library
Ytterbium triflate catalysed domino reaction of (3‐formyl‐4‐indolyl)‐derived donor‐acceptor
cyclopropane with primary amines provides a simple approach to an unprecedented …

Cationic [1,5]‐Aryl Migrations of Propargyl Benzyl Ethers – A Stereospecific Approach to E‐ and Z‐Tetrasubstituted Olefins

S Sadhukhan, SR Nair, B Baire - Advanced Synthesis & …, 2024 - Wiley Online Library
Herein we report the discovery and development of the first example of a cationic [1, 5]‐aryl
migration reaction, through an unprecedented phenonium ions. This reaction does not …

Ring-Opening of Donor-Acceptor Cyclopropane Diester for the Synthesis of Oxime Esters and 2, 3-Dihydroazete Ester

N Yadav, K Verma, A Das, N Kaur, P Banerjee - Synthesis, 2024 - thieme-connect.com
A simple and efficient approach for the synthesis of privileged oxime esters by employing
donor-acceptor cyclopropane diesters (DACs) as one of the potential precursors is reported …

A new activating mode of donor–acceptor cyclopropane: the tug-of-war between strain and aromaticity, transient generation of quinone methides and their reactions …

V Shorokhov, B Chabuka, T Tikhonov, A Filippova… - 2024 - chemrxiv.org
Here, we present a new approach for activation of donor-acceptor cyclopropane systems in
ring-opening reactions, which does not require the use of Lewis or Brønsted acid as a …