[HTML][HTML] Phase 2 study of dabrafenib plus trametinib in patients with BRAF V600E-mutant metastatic NSCLC: updated 5-year survival rates and genomic analysis

D Planchard, B Besse, HJM Groen… - Journal of Thoracic …, 2022 - Elsevier
Introduction Dabrafenib plus trametinib was found to have robust antitumor activity in
patients with BRAF V600E-mutant metastatic NSCLC (mNSCLC). We report updated …

Spruce giga‐genomes: structurally similar yet distinctive with differentially expanding gene families and rapidly evolving genes

KK Gagalova, RL Warren, L Coombe, J Wong… - The Plant …, 2022 - Wiley Online Library
Spruces (Picea spp.) are coniferous trees widespread in boreal and mountainous forests of
the northern hemisphere, with large economic significance and enormous contributions to …

[HTML][HTML] Early-stage economic analysis of research-based comprehensive genomic sequencing for advanced cancer care

D Weymann, J Laskin, SJM Jones, R Roscoe… - Journal of Community …, 2022 - Springer
Genomic research is driving discovery for future population benefit. Limited evidence exists
on immediate patient and health system impacts of research participation. This study uses …

[PDF][PDF] Genomic sequencing to guide cancer management

J Oristaglio, M Manso-Share, P Madireddi, B Wilkinson… - 2021 - ecwebmaster.com
Genomic testing is a critical component of precision medicine. It has influenced many
aspects of patient care, including diagnosis, disease monitoring, and treatment choice …

[HTML][HTML] Novartis announces Tabrecta® first published overall survival and updated overall response data in patients with METex14 metastatic NSCLC Folgen

NEL ASA, A SE - markets.ft.com
Tabrecta is the first therapy approved by the FDA to specifically target metastatic non-small
cell lung cancer (NSCLC) with a mutation that leads to MET exon 14 skipping …

[HTML][HTML] Ulkoasun asetukset Uutta

KL Nyt, KL Oma - Hypertension (high blood pressure) - kauppalehti.fi
Basel, March 24, 2020–AveXis, a Novartis company, today announced a one-time infusion
of Zolgensma®(onasemnogene abeparvovec-xioi) showed rapid, significant and clinically …

[引用][C] Big Data and Me: History, Advances and the Clinical Significance of Genomics

P Manning