Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is
responsible for a worldwide pandemic. Given the global health emergency, drug …

This is a sequel to the previous Perspective “The CH–π hydrogen bond in chemistry.
Conformation, supramolecules, optical resolution and interactions involving carbohydrates” …

The plasma membrane of eukaryotic cells contains several types of lipids displaying high
biochemical variability in both their apolar moiety (eg, the acyl chain of glycerolipids) and …

Objectives the Covid-19 pandemic has been marked by sudden outbreaks of SARS-CoV-2
variants harboring mutations in both the N-terminal (NTD) and receptor binding (RBD) …

The emergence of SARS-coronavirus-2 (SARS-CoV-2) has led to a global pandemic
disease referred to as coronavirus disease 19 (COVID-19). Hydroxychloroquine (CLQ …

Alzheimer's disease (AD) is a neurodegenerative disorder that is one of the most
devastating and widespread diseases worldwide, mainly affecting the aging population. One …

Alzheimer's disease (AD), the most common neurodegenerative disorder associated with
dementia, is typified by the pathological accumulation of amyloid Aβ peptides and …

Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary
pathologic species in Alzheimer's and Parkinson's diseases. However, the molecular …