Copy number alterations are widespread in cancer genomes and are part of the genomic
instability underlying the pathogenesis of neoplastic diseases. Recurrent copy number …

DNA that controls gene expression (eg enhancers, promoters) has seemed almost never to
be conserved between distantly related animals, like vertebrates and arthropods. This is …

Abstract Background/Aims: Zinc finger protein 703 (ZNF703), initially identified as a novel
oncogene in human breast cancer, is a member of the NET/NlZ family of zinc finger …

Zinc finger proteins (ZNFs) belong to the NET/NLZ protein family. In physiological functions,
ZNF703 play significant roles in embryonic development, especially in the nervous system …

Gene regulatory networks (GRNs) evolve as a result of the coevolutionary processes acting
on transcription factors (TFs) and the cis-regulatory modules they bind. The zinc-finger TF …

Zinc finger protein ZNF503 is an important regulator during developmental process and
tumor initiation. ZNF503 drives tumor development and process and was cancer-specific …

Morphological development of the lung requires complex signal crosstalk between the
mesenchymal and epithelial progenitors. Elucidating the genetic cascades underlying signal …

The transcription factors Pax3 and Zic1 are critical to specify the neural plate border and to
promote neural crest formation. In a microarray screen designed to identify genes regulated …

Abstract Zinc finger protein 703 (ZNF703) is a new member of the zinc finger protein family
of transcription factors that plays an important role during embryogenesis in metazoans. The …

Juvenile hormone and ecdysone are key regulators in the metamorphosis and development.
Grocho (Gro) is a highly conserved protein required for metamorphosis and development …