The last two decades of genome‐scale research revealed a complex molecular picture of
acute myeloid leukemia (AML). On the one hand, a number of mutations were discovered …

Acute myeloid leukemia is an aggressive hematopoietic stem cell malignancy with poor
outcomes despite the available treatment options including standard chemotherapy …

This research sought to elucidate the mechanism underlying the self-renewal capacity of
leukemic stem cells (LSCs) to offer new insights into the treatment of acute myeloid leukemia …

Acute myeloid leukemia (AML) is a group of heterogeneous hematological malignancies.
We identified key genes as ITGAM and lncRNA ITGB2-AS1 through different bioinformatics …

Background Adipose tissue-derived stem cells (ASCs) have important clinical significance
as regulators of skin scar tissue regeneration. ASCs inhibit keloid formation and increase …

Acute myelogenous leukemia (AML) is an aggressive hematological malignancy. The
pathophysiology of the disease depends on cytogenetic abnormalities, gene mutations …

Ribonucleoproteins (RNPs) are frequently applied for therapeutic gene editing as well as
fundamental research because the method is fast, viral free, and shows fewest off target …

Haematopoietic stem and progenitor cells (HSPCs) are defined as unspecialized cells that
give rise to more differentiated cells. In a similar way, leukaemic stem and progenitor cells …

Abstract Treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA)
in combination with low doses of arsenic trioxide or chemotherapy leads to exceptionally …

Testicular germ cell tumors (TGCTs) represent a well curable malignity due to their
exceptional response to cisplatin (CDDP). Despite remarkable treatment results …