Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare

P Suravajhala, LJA Kogelman… - Genetics Selection …, 2016 - Springer
In the past years, there has been a remarkable development of high-throughput omics (HTO)
technologies such as genomics, epigenomics, transcriptomics, proteomics and …

Equine performance genes and the future of doping in horseracing

T Wilkin, A Baoutina, N Hamilton - Drug testing and analysis, 2017 - Wiley Online Library
A horse's success on the racetrack is determined by genetics, training and nutrition, and
their translation into physical traits such as speed, endurance and muscle strength …

Microbiome and blood analyte differences point to community and metabolic signatures in lean and obese horses

AS Biddle, JF Tomb, Z Fan - Frontiers in veterinary science, 2018 - frontiersin.org
Due to modern management practices and the availability of energy dense feeds, obesity is
a serious and increasingly common health problem for horses. Equine obesity is linked to …

RNA-sequencing: a tool to explore new frontiers in animal genetics

S Wickramasinghe, A Cánovas, G Rincón, JF Medrano - Livestock Science, 2014 - Elsevier
Global gene expression profiling by RNA-Sequencing (RNA-Seq) was introduced in 2004
with the advent of next generation sequencing technologies and has made a revolutionary …

High-intensity aerobic exercise suppresses cancer growth by regulating skeletal muscle-derived oncogenes and tumor suppressors

H Jee, E Park, K Hur, M Kang, Y Kim - Frontiers in Molecular …, 2022 - frontiersin.org
High-intensity aerobic exercise (90% of the maximal heart rate) can effectively suppress
cancer cell proliferation in vivo. However, the molecular effects of exercise and its relevance …

In-depth duodenal transcriptome survey in chickens with divergent feed efficiency using RNA-Seq

G Yi, J Yuan, H Bi, W Yan, N Yang, L Qu - PloS one, 2015 - journals.plos.org
Since the feed cost is a major determinant of profitability in poultry industry, how to improve
feed efficiency through genetic selection is an intriguing subject for breeders and producers …

De Novo Transcriptome Assembly of the Chinese Swamp Buffalo by RNA Sequencing and SSR Marker Discovery

T Deng, C Pang, X Lu, P Zhu, A Duan, Z Tan, J Huang… - PLoS …, 2016 - journals.plos.org
The Chinese swamp buffalo (Bubalis bubalis) is vital to the lives of small farmers and has
tremendous economic importance. However, a lack of genomic information has hampered …

Exercise-induced modification of the skeletal muscle transcriptome in Arabian horses

K Ropka-Molik, M Stefaniuk-Szmukier… - Physiological …, 2017 - journals.physiology.org
It has been found that Arabian and Thoroughbred horses differ in muscle fiber structure and
thus in physiological changes occurring in muscles during exercise. The aim of the present …

Molecular insights into the lipid‐carbohydrates metabolism switch under the endurance effort in Arabian horses

G Myćka, K Ropka‐Molik, A Cywińska… - Equine Veterinary …, 2024 - Wiley Online Library
Background Recent studies have shown that in Arabian horse muscle, long‐term exercise‐
induced expression of genes related to fatty acid degradation and the downregulation of …

Genome-wide analysis of DNA methylation patterns in horse

JR Lee, CP Hong, JW Moon, YD Jung, DS Kim, TH Kim… - BMC genomics, 2014 - Springer
Background DNA methylation is an epigenetic regulatory mechanism that plays an essential
role in mediating biological processes and determining phenotypic plasticity in organisms …