Differentiation of mesenchymal stem cells for cartilage tissue engineering: Individual and synergetic effects of three-dimensional environment and mechanical loading
Chondrogenesis of dedifferentiated chondrocytes and mesenchymal stem cells is influenced
not only by soluble molecules like growth factors, but also by the cell environment itself. The …
not only by soluble molecules like growth factors, but also by the cell environment itself. The …
Soluble eggshell membrane: a natural protein to improve the properties of biomaterials used for tissue engineering applications
Extracellular matrix (ECM) acts as an instructing template for the cells contained in tissues. It
plays a vital role in regulating cellular behavior by holding and interacting with various …
plays a vital role in regulating cellular behavior by holding and interacting with various …
Biomimetic biphasic scaffolds in osteochondral tissue engineering: Their composition, structure and consequences
A Banihashemian, SZ Benisi, S Hosseinzadeh… - Acta …, 2023 - Elsevier
Approaches to the design and construction of biomimetic scaffolds for osteochondral tissue,
show increasing advances. Considering the limitations of this tissue in terms of repair and …
show increasing advances. Considering the limitations of this tissue in terms of repair and …
Injectable gelatin/glucosamine cryogel microbeads as scaffolds for chondrocyte delivery in cartilage tissue engineering
YH Huang, HA Chen, CH Chen, HT Liao… - International Journal of …, 2023 - Elsevier
In this study, we fabricate squeezable cryogel microbeads as injectable scaffolds for
minimum invasive delivery of chondrocytes for cartilage tissue engineering applications. The …
minimum invasive delivery of chondrocytes for cartilage tissue engineering applications. The …
[HTML][HTML] mTOR: a potential therapeutic target in osteoarthritis?
B Pal, H Endisha, Y Zhang, M Kapoor - Drugs in R&D, 2015 - Springer
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the progressive
loss of articular cartilage, remodeling of the subchondral bone, and synovial inflammation …
loss of articular cartilage, remodeling of the subchondral bone, and synovial inflammation …
Interplay of reactive oxygen species (ROS) and tissue engineering: a review on clinical aspects of ROS-responsive biomaterials
N Tyagi, K Gambhir, S Kumar, G Gangenahalli… - Journal of Materials …, 2021 - Springer
Reactive oxygen species (ROS) refers to the reactive molecules and free radicals of oxygen
generated as the by-products of aerobic respiration. Historically, ROS are known as stress …
generated as the by-products of aerobic respiration. Historically, ROS are known as stress …
Engineering fiber anisotropy within natural collagen hydrogels
It is well known that biophysical properties of the extracellular matrix (ECM), including
stiffness, porosity, composition, and fiber alignment (anisotropy), play a crucial role in …
stiffness, porosity, composition, and fiber alignment (anisotropy), play a crucial role in …
Fabrication of porous scaffolds with decellularized cartilage matrix for tissue engineering application
B Nasiri, S Mashayekhan - Biologicals, 2017 - Elsevier
Due to the avascular nature of articular cartilage, damaged tissue has little capacity for
spontaneous healing. Three-dimensional scaffolds have potential for use in tissue …
spontaneous healing. Three-dimensional scaffolds have potential for use in tissue …
[HTML][HTML] Progress in composite hydrogels and scaffolds enriched with icariin for osteochondral defect healing
Osteochondral structure reconstruction by tissue engineering, a challenge in regenerative
medicine, requires a scaffold that ensures both articular cartilage and subchondral bone …
medicine, requires a scaffold that ensures both articular cartilage and subchondral bone …
[HTML][HTML] A biphasic hydrogel with self-healing properties and a continuous layer structure for potential application in osteochondral defect repair
Y Jiang, S Guo, J Jiao, L Li - Polymers, 2023 - mdpi.com
The treatment of osteochondral defects remains challenging due to the limited healing
capacity of cartilage and the poor results of traditional methods. Inspired by the structure of …
capacity of cartilage and the poor results of traditional methods. Inspired by the structure of …