BACKGROUND Recent progress in the formation of artificial gametes, ie gametes generated
by manipulation of their progenitors or of somatic cells, has led to scientific and societal …

Abstract BACKGROUND Mitochondrial DNA (mtDNA) disorders are an important cause of
human diseases. In view of the limitations of prenatal diagnosis and preimplantation genetic …

A series of recent scientific results suggest that, in the not-too-distant future, it will be
possible to create viable human gametes from human stem cells. This paper discusses the …

In this review we aim to provide an overview of the most important ethical pros and cons of
stem cell derived gametes (SCD-gametes), as a contribution to the debate about …

Most people believe that parents have rights to direct their children's education and
upbringing. But why? What grounds those rights? How broad is their scope? Can we defend …

In 2015, two novel in vitro fertilisation techniques intended to prevent the inheritance of
mitochondrial disease were legalised in the United Kingdom, following an intense period of …

BACKGROUND Recent progress in the formation of artificial gametes, ie gametes generated
from progenitors or somatic cells, has led to scientific and societal discussion about their use …

Research question How much do patients with severe infertility and their gynaecologists
value genetic parenthood relative to other key treatment characteristics? Design A discrete …

The derivation of gametes from patient-specific pluripotent stem cells may provide new
perspectives for genetic parenthood for patients currently facing sterility. We use current data …

It has been suggested that future application of stem-cell derived gametes (SCD-gametes)
might lead to the possibility for same-sex couples to have genetically related children. Still …