UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies

ME Terlizzi, G Gribaudo, ME Maffei - Frontiers in microbiology, 2017 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …

[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides

Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …

The nature of immune responses to urinary tract infections

SN Abraham, Y Miao - Nature Reviews Immunology, 2015 - nature.com
The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …

[HTML][HTML] Urinary tract infection in pediatrics: an overview

EA Oliveira, RH Mak - Jornal de pediatria, 2020 - SciELO Brasil
Objective This review aimed to provide a critical overview on the pathogenesis, clinical
findings, diagnosis, imaging investigation, treatment, chemoprophylaxis, and complications …

The clinical diagnosis and management of urinary tract infections in children and adolescents

L Korbel, M Howell, JD Spencer - Paediatrics and international …, 2017 - Taylor & Francis
Urinary tract infections (UTI) are one of the most common and serious bacterial infections
encountered by paediatricians and primary care physicians. Although the diagnosis and …

Design of antimicrobial peptides: progress made with human cathelicidin LL-37

G Wang, JL Narayana, B Mishra, Y Zhang… - … Peptides: Basics for …, 2019 - Springer
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …

The immune response to infection in the bladder

L Lacerda Mariano, MA Ingersoll - Nature Reviews Urology, 2020 - nature.com
The bladder is continuously protected by passive defences such as a mucus layer,
antimicrobial peptides and secretory immunoglobulins; however, these defences are …

The diagnosis, evaluation and treatment of acute and recurrent pediatric urinary tract infections

B Becknell, M Schober, L Korbel… - Expert review of anti …, 2015 - Taylor & Francis
Urinary tract infection (UTI) is one of the most common bacterial infections encountered by
pediatricians. Currently, the diagnosis and management of acute UTI and recurrent UTI in …

Biofilm formation, antimicrobial susceptibility and virulence genes of Uropathogenic Escherichia coli isolated from clinical isolates in Uganda

P Katongole, F Nalubega, NC Florence… - BMC Infectious …, 2020 - Springer
Introduction Uropathogenic E. coli is the leading cause of Urinary tract infections (UTIs),
contributing to 80–90% of all community-acquired and 30–50% of all hospital-acquired UTIs …

[HTML][HTML] The urinary microbiome and biological therapeutics: Novel therapies for urinary tract infections

C Kenneally, CP Murphy, RD Sleator… - Microbiological …, 2022 - Elsevier
The discovery of microbial communities in the urinary tract (the urobiome) has fundamentally
altered the previous doctrine regarding urine sterility and associated urinary disorders …