The role of cholesterol in membrane fusion

ST Yang, AJB Kreutzberger, J Lee, V Kiessling… - Chemistry and physics …, 2016 - Elsevier
Cholesterol modulates the bilayer structure of biological membranes in multiple ways. It
changes the fluidity, thickness, compressibility, water penetration and intrinsic curvature of …

[HTML][HTML] Coating materials to increase the stability of liposomes

D Pasarin, AI Ghizdareanu, CE Enascuta, CB Matei… - Polymers, 2023 - mdpi.com
Liposomes carry various compounds with applications in pharmaceutical, food, and
cosmetic fields, and the administration route is especially parenteral, oral, or transdermal …

Morphological, enzymatic screening, and phylogenetic analysis of thermophilic bacilli isolated from five hot springs of Myagdi, Nepal

P Yadav, S Korpole, GS Prasad, G Sahni… - Journal of Applied …, 2018 - jabonline.in
The present study was conducted to identify and characterize the thermophilic bacteria
isolated from five hot springs, namely, Sinkosh, Singha, Bhurung, Ratopani, and Paudwar …

[PDF][PDF] Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry

J Lee, AJB Kreutzberger, L Odongo, EA Nelson… - Biophysical …, 2021 - cell.com
Cholesterol serves critical roles in enveloped virus fusion by modulating membrane
biophysical properties. The glycoprotein (GP) of Ebola virus (EBOV) promotes fusion in the …

[HTML][HTML] Modulation of lipid vesicle–membrane interactions by cholesterol

CP Chng, KJ Hsia, C Huang - Soft Matter, 2022 - pubs.rsc.org
Nanoscale lipid vesicles are attractive vehicles for drug delivery. Although often considered
as soft nanoparticles in terms of mechanical deformability, the fluidic nature of the lipid …

[PDF][PDF] Single-virus content-mixing assay reveals cholesterol-enhanced influenza membrane fusion efficiency

KN Liu, SG Boxer - Biophysical Journal, 2021 - cell.com
To infect a cell, enveloped viruses must first undergo membrane fusion, which proceeds
through a hemifusion intermediate, followed by the formation of a fusion pore through which …

A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach.

I Sopyan, D Gozali - Systematic Reviews in Pharmacy, 2020 - search.ebscohost.com
Drug encapsulation in liposomes has provided an opportunity to improve therapeutic drugs
mainly through changes in biodistribution and targeting of drugs to certain tissues. The role …

Biophysical studies of lipid nanodomains using different physical characterization techniques

JJ Kinnun, HL Scott, D Bolmatov, CP Collier… - Biophysical …, 2023 - cell.com
For the past 50 years, evidence for the existence of functional lipid domains has been
steadily accumulating. Although the notion of functional lipid domains, also known as" lipid …

[PDF][PDF] Membrane hydrophobicity determines the activation free energy of passive lipid transport

JR Rogers, GE Garcia, PL Geissler - Biophysical journal, 2021 - cell.com
The collective behavior of lipids with diverse chemical and physical features determines a
membrane's thermodynamic properties. Yet, the influence of lipid physicochemical …

Camptothecin-loaded fusogenic nanodroplets as ultrasound theranostic agent in stem cell-mediated drug-delivery system

YJ Ho, YJ Chiang, ST Kang, CH Fan, CK Yeh - Journal of controlled release, 2018 - Elsevier
Adipose-derived stem cells (ADSCs) have been utilized in cellular delivery systems to carry
therapeutic agents into tumors by migration. Drug-loaded nanodroplets release drugs and …