Nucleus accumbens dopamine is known to play a role in motivational processes, and
dysfunctions of mesolimbic dopamine may contribute to motivational symptoms of …

Midbrain dopamine neurons are well known for their strong responses to rewards and their
critical role in positive motivation. It has become increasingly clear, however, that dopamine …

Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

Motivation has been defined as the process that allows organisms to regulate their internal
and external environment, and control the probability, proximity and availability of stimuli. As …

Individuals make choices and prioritize goals using complex processes that assign value to
rewards and associated stimuli. During Pavlovian learning, previously neutral stimuli that …

Drug addiction is increasingly viewed as the endpoint of a series of transitions from initial
drug use—when a drug is voluntarily taken because it has reinforcing, often hedonic, effects …

Introduction Debate continues over the precise causal contribution made by mesolimbic
dopamine systems to reward. There are three competing explanatory categories:'liking' …

An increasingly popular method of assessing cognitive functions in rodents is the automated
touchscreen platform, on which a number of different cognitive tests can be run in a manner …

Anatomical and functional refinements of the meso-limbic dopamine system of the rat are
discussed. Present experiments suggest that dopaminergic neurons localized in the …

The dopamine system has been linked to anhedonia in depression and both the positive
and negative symptoms of schizophrenia, but it remains unclear how dopamine dysfunction …