An integrated model of the recognition of Candida albicans by the innate immune system

MG Netea, GD Brown, BJ Kullberg… - Nature Reviews …, 2008 - nature.com
The innate immune response was once considered to be a limited set of responses that
aimed to contain an infection by primitive'ingest and kill'mechanisms, giving the host time to …

Production and function of cytokines in natural and acquired immunity to Candida albicans infection

RB Ashman, JM Papadimitriou - Microbiological reviews, 1995 - Am Soc Microbiol
Host resistance against infections caused by the yeast Candida albicans is mediated
predominantly by polymorphonuclear leukocytes and macrophages. Antigens of Candida …

Antibodies to interleukin 12 abrogate established experimental colitis in mice.

MF Neurath, I Fuss, BL Kelsall, E Stüber… - The Journal of …, 1995 - rupress.org
In this study, we describe a novel murine model of chronic intestinal inflammation induced
by the hapten reagent 2, 4, 6-trinitrobenzene sulfonic acid (TNBS). Rectal application of low …

Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats

F De Bernardis, M Boccanera, D Adriani… - Infection and …, 1997 - Am Soc Microbiol
The role of antibodies (Abs) in the resistance to vaginal infection by Candida albicans was
investigated by using a rat vaginitis model. Animals receiving antimannoprotein (anti-MP) …

Extracellular vesicle-associated transitory cell wall components and their impact on the interaction of fungi with host cells

L Nimrichter, MM De Souza, M Del Poeta… - Frontiers in …, 2016 - frontiersin.org
Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …

Elevated aspartic proteinase secretion and experimental pathogenicity of Candida albicans isolates from oral cavities of subjects infected with human …

F De Bernardis, P Chiani, M Ciccozzi… - Infection and …, 1996 - Am Soc Microbiol
Isolates of Candida albicans from the oral cavities of subjects at different stages of human
immunodeficiency virus (HIV) infection or uninfected controls were examined for (i) …

MP1 Encodes an Abundant and Highly Antigenic Cell Wall Mannoprotein in the Pathogenic Fungus Penicillium marneffei

L Cao, C Chan, C Lee, S Sai-yin Wong… - Infection and …, 1998 - Am Soc Microbiol
We cloned the MP1 gene, which encodes an abundant antigenic cell wall mannoprotein
from the dimorphic pathogenic fungus Penicillium marneffei. MP1 is a unique gene without …

Mannoproteins from Cryptococcus neoformans Promote Dendritic Cell Maturation and Activation

D Pietrella, C Corbucci, S Perito, G Bistoni… - Infection and …, 2005 - Am Soc Microbiol
Our previous data show that mannoproteins (MPs) from Cryptococcus neoformans are able
to induce protective responses against both C. neoformans and Candida albicans. Here we …

Interplay between Protective and Inhibitory Antibodies Dictates the Outcome of Experimentally Disseminated Candidiasis in Recipients of a Candida albicans …

C Bromuro, A Torosantucci, P Chiani, S Conti… - Infection and …, 2002 - Am Soc Microbiol
Mice immunized with heat-inactivated, whole yeast-form cells (Y cells) of Candida albicans
developed intense, specific humoral and cell-mediated immune responses. However, they …

The 65 kDa mannoprotein gene of Candida albicans encodes a putative β‐glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity

S Sandini, R La Valle, F De Bernardis… - Cellular …, 2007 - Wiley Online Library
Mannoproteins are fungal cell wall components which play a main role in host–parasite
relationship. Camp65p is a putative β‐glucanase mannoprotein of 65 kDa which has been …