The role of CXCL16 in the pathogenesis of cancer and other diseases

J Korbecki, K Bajdak-Rusinek, P Kupnicka… - International journal of …, 2021 - mdpi.com
CXCL16 is a chemotactic cytokine belonging to the α-chemokine subfamily. It plays a
significant role in the progression of cancer, as well as the course of atherosclerosis, renal …

Biological aging in people living with HIV on successful antiretroviral therapy: do they age faster?

SS Akusjärvi, U Neogi - Current HIV/AIDS Reports, 2023 - Springer
Abstract Purpose of Review In the absence of a prophylactic/therapeutic vaccine or cure, the
most amazing achievement in the battle against HIV was the discovery of effective, well …

Gut microbiota, circulating inflammatory markers and metabolites, and carotid artery atherosclerosis in HIV infection

Z Wang, BA Peters, MK Bryant, DB Hanna, T Schwartz… - Microbiome, 2023 - Springer
Background Alterations in gut microbiota have been implicated in HIV infection and
cardiovascular disease. However, how gut microbial alterations relate to host inflammation …

[HTML][HTML] ggVolcanoR: A Shiny app for customizable visualization of differential expression datasets

KA Mullan, LM Bramberger, PR Munday… - Computational and …, 2021 - Elsevier
Volcano and other analytical plots (eg, correlation plots, upset plots, and heatmaps) serve as
important data visualization methods for transcriptomic and proteomic analyses …

Immune checkpoints as the immune system regulators and potential biomarkers in HIV-1 infection

M Sperk, R Domselaar, U Neogi - International journal of molecular …, 2018 - mdpi.com
Immune checkpoints are several co-stimulatory and inhibitory pathways that regulate T cell
immune responses. Most of the discoveries about immune checkpoints were made in cancer …

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target

U Neogi, N Elaldi, S Appelberg, A Ambikan, E Kennedy… - Elife, 2022 - elifesciences.org
The pathogenesis and host-viral interactions of the Crimean–Congo hemorrhagic fever
orthonairovirus (CCHFV) are convoluted and not well evaluated. Application of the multi …

Therapeutic vaccine in chronically HIV-1-infected patients: a randomized, double-blind, placebo-controlled phase IIa trial with HTI-TriMix

W de Jong, L Leal, J Buyze, P Pannus, A Guardo… - Vaccines, 2019 - mdpi.com
Therapeutic vaccinations aim to re-educate human immunodeficiency virus (HIV)-1-specific
immune responses to achieve durable control of HIV-1 replication in virally suppressed …

Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist

M Sperk, AT Ambikan, S Ray, K Singh… - Journal of …, 2021 - Am Soc Microbiol
ABSTRACT HIV-1 elite controllers (EC) are a rare group among HIV-1-infected individuals
who can naturally control viral replication for a prolonged period. Due to their …

Unique phenotypic characteristics of recently transmitted HIV-1 subtype C envelope glycoprotein gp120: use of CXCR6 coreceptor by transmitted founder viruses

M Ashokkumar, SG Aralaguppe, SP Tripathy… - Journal of …, 2018 - Am Soc Microbiol
Adequate information on the precise molecular and biological composition of the viral
strains that establish HIV infection in the human host will provide effective means of …

[HTML][HTML] High-throughput proteomic analysis reveals systemic dysregulation in virally suppressed people living with HIV

N Vadaq, Y Zhang, WAJW Vos, AL Groenendijk… - JCI insight, 2023 - ncbi.nlm.nih.gov
BACKGROUND People living with HIV (PLHIV) receiving antiretroviral therapy (ART) exhibit
persistent immune dysregulation and microbial dysbiosis, leading to development of …