Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

Pulmonary fibrosis and architectural remodeling of tissues can severely disrupt lung
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied …

Zinc is essential to all forms of life, 1-4 with an average adult human containing ca. 3 g of
zinc. 5 For example, zinc is indispensable for effective growth and development, has …

An essential feature of a healed wound is the restoration of an intact epidermal barrier
through wound epithelialization, also known as re-epithelialization. The directed migration of …

Wound repair is initiated with the aggregation of platelets, formation of a fibrin clot, and
release of growth factors from the activated coagulation pathways, injured cells, platelets …

Abstract Aims Matrix metalloproteinases (MMPs) play a major role in wound healing: they
can degrade all components of the extracellular matrix. In diabetic foot ulcers there is an …

Keratinocyte mobilization is a critical aspect of wound re-epithelialization, but the
mechanisms that control its precise regulation remain poorly understood. We set out to test …

During wound-healing, cells are required to migrate rapidly into the wound site via a
proteolytically generated pathway in the provisional matrix, to produce new extracellular …

Following tissue damage, host wound healing ensues. This process requires an elaborate
interplay between numerous cell types which orchestrate a series of regulated and …

Background A keloid is a specific skin lesion that expands beyond the boundaries of the
original injury as it heals. Histologically, it is characterized by the excessive accumulation of …