Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease

R Micha, F Imamura, MW von Ballmoos… - The American journal of …, 2011 - Elsevier
Inflammation predicts risk for cardiovascular disease (CVD) events, but the relation of drugs
that directly target inflammation with CVD risk is not established. Methotrexate is a disease …

Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE

DPM Symmons, SE Gabriel - Nature Reviews Rheumatology, 2011 - nature.com
The excess risk of cardiovascular disease (CVD) associated with inflammatory rheumatic
diseases has long been recognized. Patients with established rheumatoid arthritis (RA) or …

The risk of myocardial infarction in rheumatoid arthritis and diabetes mellitus: a Danish nationwide cohort study

J Lindhardsen, O Ahlehoff, GH Gislason… - Annals of the …, 2011 - ard.bmj.com
Objectives To examine in a nationwide cohort whether the risk of myocardial infarction (MI)
in patients with rheumatoid arthritis (RA) is comparable to the risk in patients with diabetes …

Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study

A Naranjo, T Sokka, MA Descalzo, J Calvo-Alén… - Arthritis research & …, 2008 - Springer
Introduction We analyzed the prevalence of cardiovascular (CV) disease in patients with
rheumatoid arthritis (RA) and its association with traditional CV risk factors, clinical features …

Initiation of tumor necrosis factor-α antagonists and the risk of hospitalization for infection in patients with autoimmune diseases

CG Grijalva, L Chen, E Delzell, JW Baddley… - Jama, 2011 - jamanetwork.com
Context Although tumor necrosis factor (TNF)-α antagonists are increasingly used in place of
nonbiologic comparator medications, their safety profile remains incomplete. Objectives To …

Tumour necrosis factor antagonist use and associated risk reduction of cardiovascular events among patients with rheumatoid arthritis

JD Greenberg, JM Kremer, JR Curtis… - Annals of the …, 2011 - ard.bmj.com
Objective To examine the association of cardiovascular events with tumour necrosis factor
(TNF) α antagonist use compared with non-biological disease-modifying antirheumatic drug …

Validity of myocardial infarction diagnoses in administrative databases: a systematic review

N McCormick, D Lacaille, V Bhole, JA Avina-Zubieta - PloS one, 2014 - journals.plos.org
Background Though administrative databases are increasingly being used for research
related to myocardial infarction (MI), the validity of MI diagnoses in these databases has …

Comparative risk of cardiovascular events with biologic and synthetic disease‐modifying antirheumatic drugs in patients with rheumatoid arthritis: a systematic review …

S Singh, M Fumery, AG Singh, N Singh… - Arthritis care & …, 2020 - Wiley Online Library
Objective We performed a systematic review and meta‐analysis to evaluate the comparative
effects of tumor necrosis factor inhibitors (TNF i), non‐TNF i biologics, and conventional …

Explaining the cardiovascular risk associated with rheumatoid arthritis: traditional risk factors versus markers of rheumatoid arthritis severity

DH Solomon, J Kremer, JR Curtis… - Annals of the …, 2010 - ard.bmj.com
Background Cardiovascular (CV) disease has a major impact on patients with rheumatoid
arthritis (RA), however, the relative contributions of traditional CV risk factors and markers of …

Short-term dose and duration-dependent glucocorticoid risk for cardiovascular events in glucocorticoid-naive patients with rheumatoid arthritis

AJ Ocon, G Reed, DA Pappas, JR Curtis… - Annals of the rheumatic …, 2021 - ard.bmj.com
Objectives Rheumatoid arthritis (RA), along with glucocorticoid use, is associated with
cardiovascular disease. Cardiovascular safety of glucocorticoids in RA is controversial and …