Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis
Objectives The acute respiratory distress syndrome (ARDS) secondary to viral pneumonitis
is one of the main causes of high mortality in patients with COVID-19 (novel coronavirus …
is one of the main causes of high mortality in patients with COVID-19 (novel coronavirus …
[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19
T Herold, V Jurinovic, C Arnreich, BJ Lipworth… - Journal of Allergy and …, 2020 - Elsevier
Background Coronavirus disease 2019 (COVID-19) can manifest as a viral-induced
hyperinflammation with multiorgan involvement. Such patients often experience rapid …
hyperinflammation with multiorgan involvement. Such patients often experience rapid …
[HTML][HTML] Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome
LB Afrin, LB Weinstock, GJ Molderings - International journal of infectious …, 2020 - Elsevier
Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …
Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician …
M Gianfrancesco, KL Hyrich, S Al-Adely… - Annals of the …, 2020 - ard.bmj.com
Objectives COVID-19 outcomes in people with rheumatic diseases remain poorly
understood. The aim was to examine demographic and clinical factors associated with …
understood. The aim was to examine demographic and clinical factors associated with …
Coronavirus disease 2019, superinfections, and antimicrobial development: what can we expect?
CJ Clancy, MH Nguyen - Clinical Infectious Diseases, 2020 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) arose at a time of great concern about
antimicrobial resistance (AMR). No studies have specifically assessed COVID-19 …
antimicrobial resistance (AMR). No studies have specifically assessed COVID-19 …
Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study
Objectives The impact of inflammatory rheumatic diseases on COVID-19 severity is poorly
known. Here, we compare the outcomes of a cohort of patients with rheumatic diseases with …
known. Here, we compare the outcomes of a cohort of patients with rheumatic diseases with …
Clinical characteristics and outcomes of critically ill patients with novel coronavirus infectious disease (COVID-19) in China: a retrospective multicenter study
J Xie, W Wu, S Li, Y Hu, M Hu, J Li, Y Yang… - Intensive care …, 2020 - Springer
Purpose An ongoing outbreak of coronavirus disease 2019 (COVID-19) emerged in Wuhan
since December 2019 and spread globally. However, information about critically ill patients …
since December 2019 and spread globally. However, information about critically ill patients …
Impact of the COVID-19 pandemic on clinical research
KR Tuttle - Nature Reviews Nephrology, 2020 - nature.com
The COVID-19 pandemic has placed a tremendous strain on sustaining the clinical research
enterprise and will also likely affect key study outcomes; these effects must be considered …
enterprise and will also likely affect key study outcomes; these effects must be considered …
A physiological approach to understand the role of respiratory effort in the progression of lung injury in SARS-CoV-2 infection
Deterioration of lung function during the first week of COVID-19 has been observed when
patients remain with insufficient respiratory support. Patient self-inflicted lung injury (P-SILI) …
patients remain with insufficient respiratory support. Patient self-inflicted lung injury (P-SILI) …