Review of advances in electrospinning-based strategies for spinal cord regeneration

Y Li, T Dong, Z Li, S Ni, F Zhou, OA Alimi, S Chen… - Materials Today …, 2022 - Elsevier
Spinal cord injury (SCI) is a devastating neurological condition, commonly leading to
physical and mental deficiencies, pain, other complications, and even death. Most recently …

[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

CM Walsh, JK Wychowaniec, DF Brougham… - Pharmacology & …, 2022 - Elsevier
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …

[HTML][HTML] Primary motor cortex in Parkinson's disease: Functional changes and opportunities for neurostimulation

CF Underwood, LC Parr-Brownlie - Neurobiology of Disease, 2021 - Elsevier
Movement abnormalities of Parkinson's disease (PD) arise from disordered neural activity in
multiple interconnected brain structures. The planning and execution of movement requires …

[HTML][HTML] AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks

A Zaimi, M Wabartha, V Herman, PL Antonsanti… - Scientific reports, 2018 - nature.com
Segmentation of axon and myelin from microscopy images of the nervous system provides
useful quantitative information about the tissue microstructure, such as axon density and …

[HTML][HTML] Spinal cord stimulation in chronic neuropathic pain: mechanisms of action, new locations, new paradigms

EA Joosten, G Franken - Pain, 2020 - journals.lww.com
Neuropathic pain is a complex, heterogeneous disorder that affects approximately 8% of the
total adult human population and comes with significant burden for both the patient and …

An in vitro and ex vivo analysis of the potential of GelMA hydrogels as a therapeutic platform for preclinical spinal cord injury

CM Walsh, JK Wychowaniec, L Costello… - Advanced …, 2023 - Wiley Online Library
Spinal cord injury (SCI) is a devastating condition with no curative therapy currently
available. Immunomodulation can be applied as a therapeutic strategy to drive alternative …

[HTML][HTML] Perfusion fixation in brain banking: a systematic review

WC McFadden, H Walsh, F Richter, C Soudant… - Acta neuropathologica …, 2019 - Springer
Background Perfusing fixatives through the cerebrovascular system is the gold standard
approach in animals to prepare brain tissue for spatial biomolecular profiling, circuit tracing …

Prevascularized scaffolds bearing human dental pulp stem cells for treating complete spinal cord injury

S Guo, I Redenski, S Landau… - Advanced …, 2020 - Wiley Online Library
The regeneration of injured spinal cord is hampered by the lack of vascular supply and
neurotrophic support. Transplanting tissue‐engineered constructs with developed vascular …

Validation strategies for the interpretation of microstructure imaging using diffusion MRI

TB Dyrby, GM Innocenti, M Bech, H Lundell - Neuroimage, 2018 - Elsevier
Extracting microanatomical information beyond the image resolution of MRI would provide
valuable tools for diagnostics and neuroscientific research. A number of mathematical …

3D printing of functional bioengineered constructs for neural regeneration: A review

H Zhu, C Yao, B Wei, C Xu, X Huang… - … Journal of Extreme …, 2023 - iopscience.iop.org
Abstract 3D printing technology has opened a new paradigm to controllably and
reproducibly fabricate bioengineered neural constructs for potential applications in repairing …