One population, multiple lifestyles: commensalism and pathogenesis in the human mycobiome

DM Proctor, RA Drummond, MS Lionakis, JA Segre - Cell host & microbe, 2023 - cell.com
Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

[HTML][HTML] Genotypic diversity and unrecognized antifungal resistance among populations of Candida glabrata from positive blood cultures

H Badrane, S Cheng, CL Dupont, B Hao… - Nature …, 2023 - nature.com
The longstanding model is that most bloodstream infections (BSIs) are caused by a single
organism. We perform whole genome sequencing of five-to-ten strains from blood culture …

[HTML][HTML] Recent gene selection and drug resistance underscore clinical adaptation across Candida species

MÀ Schikora-Tamarit, T Gabaldón - Nature Microbiology, 2024 - nature.com
Understanding how microbial pathogens adapt to treatments, humans and clinical
environments is key to infer mechanisms of virulence, transmission and drug resistance …

Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial Candida glabrata isolates

E Misas, E Seagle, EN Jenkins, M Rajeev… - Journal of Clinical …, 2024 - Am Soc Microbiol
Candida glabrata is one of the most common causes of systemic candidiasis, often resistant
to antifungal medications. To describe the genomic context of emerging resistance, we …

Molecular epidemiology and antimicrobial resistance of vaginal Candida glabrata isolates in Namibia

CM Dunaiski, MM Kock, WY Chan, A Ismail… - Medical …, 2024 - academic.oup.com
Candida glabrata is the most common non-albicans Candida species that causes
vulvovaginal candidiasis (VVC). Given the intrinsically low susceptibility of C. glabrata to …

Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam

P Sephton-Clark, T Nguyen, NT Hoa, P Ashton… - Genetics, 2023 - academic.oup.com
Talaromycosis, a severe and invasive fungal infection caused by Talaromyces marneffei, is
difficult to treat and impacts those living in endemic regions of Southeast Asia, India, and …

[HTML][HTML] Whole genome analysis of echinocandin non-susceptible Candida Glabrata clinical isolates: a multi-center study in China

Y Li, X Hou, R Li, K Liao, L Ma, X Wang, P Ji, H Kong… - BMC microbiology, 2023 - Springer
Background Candida glabrata is an important cause of invasive candidiasis. Echinocandins
are the first-line treatment of invasive candidiasis caused by C. glabrata. The …

[HTML][HTML] Population genomic analyses reveal high diversity, recombination and nosocomial transmission among Candida glabrata (Nakaseomyces glabrata) isolates …

Y Wang, J Xu, F Ben Abid, H Salah… - Microbial …, 2024 - microbiologyresearch.org
Candida glabrata is a commensal yeast of the gastrointestinal tract and skin of humans.
However, it causes opportunistic infections in immunocompromised patients, and is the …

[HTML][HTML] Implication of genotypes for prognosis of Candida glabrata bloodstream infections

PY Chen, YS Huang, YC Chuang… - Journal of …, 2024 - academic.oup.com
Background Genotyping isolates of a specific pathogen may demonstrate unique patterns of
antimicrobial resistance, virulence or outcomes. However, evidence for genotype–outcome …

Whole genome sequencing reveals development of structured salmon lice (Lepeophtheirus salmonis, Krøyer, 1838) populations among aquaculture net pens through …

N Brække - 2023 - munin.uit.no
Salmon louse,(Lepeophtheirus salmonis, Krøyer, 1838), is an ectoparasite that causes
multiple health and economic problems in the farming of Atlantic salmon (Salmo salar L.) …