Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

BACKGROUND AND OBJECTIVE: Preeclampsia is an independent cardiovascular risk
factor for the mother, and recent studies reveal that offspring of affected pregnancies also …

Important protective roles of intestinal alkaline phosphatase (IAP)–including regulation of
intestinal surface pH, absorption of lipids, detoxification of free nucleotides and bacterial …

Background The association between low birth weight and adult disease is well known.
Less is known on long‐term effects of high birth weight. Objective This study aims to …

Significance: Epidemiological and animal studies have demonstrated a close link between
maternal nutrition and chronic metabolic disease in children and adults. Compelling …

Exposure to toxic environmental chemicals during pregnancy and breastfeeding is
ubiquitous and is a threat to healthy human reproduction. There are tens of thousands of …

The placenta is a transient organ found in eutherian mammals that evolved primarily to
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …

ABSTRACT A growing body of evidence highlights the importance of a mother's nutrition
from preconception through lactation in programming the emerging organ systems and …

Babies born small are at an increased risk of developing myriad adult diseases. While
growth restriction increases disease risk in all individuals, often a second hit is required to …

A growing body of evidence suggests that the intrauterine (IU) environment has a significant
and lasting effect on the long-term health of the growing fetus and the development of …