The function of neuronal circuits relies on the properties of individual neuronal cells and
their synapses. We propose that a substantial degree of synapse formation and function is …

Chemical synapses are asymmetric intercellular junctions that mediate synaptic
transmission. Synaptic junctions are organized by trans-synaptic cell adhesion molecules …

Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric
disorder that associates with prominent memory and behavioural deficits. Patients' …

The Drosophila larval neuromuscular system is relatively simple, containing only 32 motor
neurons in each abdominal hemisegment, and its neuromuscular junctions (NMJs) have …

Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …

Chemical synapses are sites of contact and information transfer between a neuron and its
partner cell. Each synapse is a specialized junction, where the presynaptic cell assembles …

Critical periods—brief intervals during which neural circuits can be modified by activity—are
necessary for proper neural circuit assembly. Extended critical periods are associated with …

The neurexin family of cell adhesion proteins consists of three members in vertebrates and
has homologs in several invertebrate species. In mammals, each neurexin gene encodes an …

Synapse assembly requires trans-synaptic signals between the pre-and postsynapse, but
our understanding of the essential organizational molecules involved in this process …

Autism spectrum disorders (ASDs) are a complex neurodevelopmental disorder that display
a triad of core behavioral deficits including restricted interests, often accompanied by …