Multi-substrate selectivity based on key loops and non-homologous domains: new insight into ALKBH family
B Xu, D Liu, Z Wang, R Tian, Y Zuo - Cellular and Molecular Life Sciences, 2021 - Springer
AlkB homologs (ALKBH) are a family of specific demethylases that depend on Fe 2+ and α-
ketoglutarate to catalyze demethylation on different substrates, including ssDNA, dsDNA …
ketoglutarate to catalyze demethylation on different substrates, including ssDNA, dsDNA …
Mammalian piRNAs: Biogenesis, function, and mysteries
Q Fu, PJ Wang - Spermatogenesis, 2014 - Taylor & Francis
Piwi-interacting RNAs (piRNAs) are a distinct class of small non-coding RNAs specifically
expressed in the germline of many species. They are most notably required for transposon …
expressed in the germline of many species. They are most notably required for transposon …
Nucleic acid oxidation in DNA damage repair and epigenetics
Methylation is a widely occurring chemical modification in nucleic acids and proteins.
Methylating agents, either extracellular or intracellular, can attack vulnerable sites in DNA …
Methylating agents, either extracellular or intracellular, can attack vulnerable sites in DNA …
Small non-coding RNAs and their associated proteins in spermatogenesis
LF Luo, CC Hou, WX Yang - Gene, 2016 - Elsevier
The importance of the gene regulation roles of small non-coding RNAs and their protein
partners is of increasing focus. In this paper, we reviewed three main small RNA species …
partners is of increasing focus. In this paper, we reviewed three main small RNA species …
Epigenome-wide analysis of piRNAs in gene-specific DNA methylation
PIWI-interacting RNAs (piRNAs) have long been associated with the silencing of
transposable elements (TEs). However, over 20,000 unique species of piRNAs mapped to …
transposable elements (TEs). However, over 20,000 unique species of piRNAs mapped to …
Developmental piRNA profiles of the invasive vector mosquito Aedes albopictus
Abstract Background In eukaryotic organisms, Piwi-interacting RNAs (piRNAs) control the
activities of mobile genetic elements and ensure genome maintenance. Recent evidence …
activities of mobile genetic elements and ensure genome maintenance. Recent evidence …
piRNAQuest: searching the piRNAome for silencers
Abstract Background PIWI-interacting RNA (piRNA) is a novel and emerging class of small
non-coding RNA (sncRNA). Ranging in length from 26-32 nucleotides, this sncRNA is a …
non-coding RNA (sncRNA). Ranging in length from 26-32 nucleotides, this sncRNA is a …
Tupaia small RNAs provide insights into function and evolution of RNAi-based transposon defense in mammals
D Rosenkranz, S Rudloff, K Bastuck, RF Ketting… - Rna, 2015 - rnajournal.cshlp.org
Argonaute proteins comprising Piwi-like and Argonaute-like proteins and their guiding small
RNAs combat mobile DNA on the transcriptional and post-transcriptional level. While Piwi …
RNAs combat mobile DNA on the transcriptional and post-transcriptional level. While Piwi …
Direct reversal repair in mammalian cells
A Ahmad, SL Nay, TR O'Connor - Adv. DNA Repair, 2015 - books.google.com
Direct reversal repair eliminates some DNA and RNA modifications without using excision,
resynthesis, and ligation. Therefore, because direct reversal repair does not require …
resynthesis, and ligation. Therefore, because direct reversal repair does not require …
The spliceosome as a transposon sensor
PA Dumesic, HD Madhani - RNA biology, 2013 - Taylor & Francis
The ability to distinguish self from non-self nucleic acids enables eukaryotes to suppress
mobile elements and maintain genome integrity. In organisms from protist to human, this …
mobile elements and maintain genome integrity. In organisms from protist to human, this …