Critical care management of chimeric antigen receptor T‐cell therapy recipients

A Shimabukuro‐Vornhagen, B Böll… - CA: a Cancer …, 2022 - Wiley Online Library
Chimeric antigen receptor (CAR) T‐cell therapy is a promising immunotherapeutic treatment
concept that is changing the treatment approach to hematologic malignancies. The …

CAR T-cell therapy and critical care: A survival guide for medical emergency teams

AS Messmer, YA Que, C Schankin, Y Banz… - Wiener klinische …, 2021 - Springer
Chimeric antigen receptor (CAR) T‑cells are genetically engineered to give T‑cells the ability
to attack specific cancer cells, and to improve outcome of patients with refractory/relapsed …

Critical illness in patients with hematologic malignancy: a population-based cohort study

BL Ferreyro, DC Scales, H Wunsch, MC Cheung… - Intensive Care …, 2021 - Springer
Purpose To describe the modern incidence and predictors of ICU admission for adult
patients newly diagnosed with a hematologic malignancy. Methods We conducted a …

Management and prevention of cellular-therapy-related toxicity: early and late complications

SR Mucha, P Rajendram - Current Oncology, 2023 - mdpi.com
Chimeric Antigen Receptor T (CAR-T) cell therapy has dramatically changed prognosis and
treatment of relapsed and refractory hematologic malignancies. Currently the 6 FDA …

Management of chimeric antigen receptor T (CAR-T) cell-associated toxicities

T Schroeder, T Martens, L Fransecky, T Valerius… - Intensive Care …, 2024 - Springer
The use of chimeric antigen receptor T (CAR-T) cells is a significant therapeutic
improvement increasing the prognosis for patients with a variety of hematological …

Extracorporeal membrane oxygenation in adults receiving haematopoietic cell transplantation: an international expert statement

M Di Nardo, G MacLaren, P Schellongowski… - The Lancet …, 2023 - thelancet.com
Combined advances in haematopoietic cell transplantation (HCT) and intensive care
management have improved the survival of patients with haematological malignancies …

Acute kidney injury in cancer immunotherapy recipients

A Joseph, A Lafarge, E Azoulay, L Zafrani - Cells, 2022 - mdpi.com
Cancer immunotherapy has now entered clinical practice and has reshaped the standard of
care for many cancer patients. With these new strategies, specific toxicities have emerged …

[HTML][HTML] Chimeric antigen receptor (CAR) T-cell therapy: harnessing extracellular vesicles for enhanced efficacy

B Spokeviciute, S Kholia, MF Brizzi - Pharmacological Research, 2024 - Elsevier
A cutting-edge approach in cell-based immunotherapy for combating resistant cancer
involves genetically engineered chimeric antigen receptor T (CAR-T) lymphocytes. In recent …

Septic shock in the immunocompromised cancer patient: a narrative review

JL Nates, F Pène, M Darmon, D Mokart, P Castro… - Critical Care, 2024 - Springer
Immunosuppressed patients, particularly those with cancer, represent a momentous and
increasing portion of the population, especially as cancer incidence rises with population …

Risk of infection in patients with hematological malignancies receiving CAR T-cell therapy: systematic review and meta-analysis

G Telli Dizman, JM Aguado… - Expert review of anti …, 2022 - Taylor & Francis
Background Chimeric antigen receptor (CAR) T-cell therapy has emerged as a promising
treatment option for relapsed or refractory B-cell malignancies and multiple myeloma …