[HTML][HTML] Cellular toxicity and immunological effects of carbon-based nanomaterials
X Yuan, X Zhang, L Sun, Y Wei, X Wei - Particle and fibre toxicology, 2019 - Springer
Background Carbon nanomaterials are a growing family of materials featuring unique
physicochemical properties, and their widespread application is accompanied by increasing …
physicochemical properties, and their widespread application is accompanied by increasing …
[HTML][HTML] Functionalised carbon nanotubes: From intracellular uptake and cell-related toxicity to systemic brain delivery
Carbon nanotubes (CNTs) have long been regarded as promising carriers in biomedicine.
Due to their high surface area and unique needle-like structure, CNTs are uniquely …
Due to their high surface area and unique needle-like structure, CNTs are uniquely …
Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells
H Chen, Y Lu, Z Cao, Q Ma, H Pi, Y Fang, Z Yu, H Hu… - Toxicology letters, 2016 - Elsevier
Cadmium (Cd) is an important and common environmental pollutant that has been linked to
cardiovascular diseases, such as atherosclerosis and hypertension. Increasing evidence …
cardiovascular diseases, such as atherosclerosis and hypertension. Increasing evidence …
[HTML][HTML] Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology
Background Several properties of multi-walled carbon nanotubes (MWCNT) have the
potential to affect their bioactivity. This study examined the in vitro and in vivo outcomes of …
potential to affect their bioactivity. This study examined the in vitro and in vivo outcomes of …
The asbestos-carbon nanotube analogy: An update
AB Kane, RH Hurt, H Gao - Toxicology and applied pharmacology, 2018 - Elsevier
Nanotechnology is an emerging industry based on commercialization of materials with one
or more dimensions of 100 nm or less. Engineered nanomaterials are currently incorporated …
or more dimensions of 100 nm or less. Engineered nanomaterials are currently incorporated …
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury
HD Jones, TR Crother… - American journal of …, 2014 - atsjournals.org
IL-1β is a potent proinflammatory cytokine that is implicated in the pathogenesis of acute
respiratory distress syndrome. We hypothesized that LPS and mechanical ventilation (MV) …
respiratory distress syndrome. We hypothesized that LPS and mechanical ventilation (MV) …
Nanomaterials and innate immunity: a perspective of the current status in nanosafety
Human exposure to engineered nanomaterials (ENMs) is inevitable due to the plethora of
applications for which they are being manufactured and integrated within. ENMs …
applications for which they are being manufactured and integrated within. ENMs …
A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment
There has been a conceptual shift in toxicological studies from describing what happens to
explaining how the adverse outcome occurs, thereby enabling a deeper and improved …
explaining how the adverse outcome occurs, thereby enabling a deeper and improved …
Nanomaterial-based scaffolds for bone tissue engineering and regeneration
G Ye, F Bao, X Zhang, Z Song, Y Liao, Y Fei… - …, 2020 - Taylor & Francis
The global incidence of bone tissue injuries has been increasing rapidly in recent years,
making it imperative to develop suitable bone grafts for facilitating bone tissue regeneration …
making it imperative to develop suitable bone grafts for facilitating bone tissue regeneration …
Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome …
F Jessop, RF Hamilton Jr, JF Rhoderick… - Toxicology and Applied …, 2017 - Elsevier
NLRP3 inflammasome activation occurs in response to hazardous particle exposures and is
critical for the development of particle-induced lung disease. Mechanisms of Lysosome …
critical for the development of particle-induced lung disease. Mechanisms of Lysosome …