Nutrigenomics, the microbiome, and gene-environment interactions: new directions in cardiovascular disease research, prevention, and treatment: a scientific …
JF Ferguson, H Allayee, RE Gerszten… - Circulation …, 2016 - Am Heart Assoc
Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …
[HTML][HTML] Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity
Obesity is associated with increased classically activated M1 adipose tissue macrophages
(ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity …
(ATMs) and decreased alternatively activated M2 ATMs, both of which contribute to obesity …
High fat diet drives obesity regardless the composition of gut microbiota in mice
S Rabot, M Membrez, F Blancher, B Berger, D Moine… - Scientific reports, 2016 - nature.com
The gut microbiota is involved in many aspects of host physiology but its role in body weight
and glucose metabolism remains unclear. Here we studied the compositional changes of …
and glucose metabolism remains unclear. Here we studied the compositional changes of …
Dynamic transcriptome and DNA methylome analyses on longissimus dorsi to identify genes underlying intramuscular fat content in pigs
Y Wang, C Ma, Y Sun, Y Li, L Kang, Y Jiang - BMC genomics, 2017 - Springer
Background The intramuscular fat content (IMF) refers to the amount of fat within muscles,
including the sum of phospholipids mainly found in cell membranes, triglycerides and …
including the sum of phospholipids mainly found in cell membranes, triglycerides and …
Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression
The present study aimed to identify genes exhibiting concomitant obesity-dependent
changes in DNA methylation and gene expression in adipose tissues in the mouse using …
changes in DNA methylation and gene expression in adipose tissues in the mouse using …
Methylation of apoptosis-associated speck-like protein with a caspase recruitment domain and outcomes in heart failure
B Butts, RA Gary, SB Dunbar, J Butler - Journal of cardiac failure, 2016 - Elsevier
Background Heart failure (HF) is associated with inflammation characterized by the
formation of the inflammasome, which triggers maturation of inflammatory cytokines …
formation of the inflammasome, which triggers maturation of inflammatory cytokines …
Analysis of Tks4 knockout mice suggests a role for Tks4 in adipose tissue homeostasis in the context of beigeing
Obesity and adipocyte malfunction are related to and arise as consequences of
disturbances in signaling pathways. Tyrosine kinase substrate with four Src homology 3 …
disturbances in signaling pathways. Tyrosine kinase substrate with four Src homology 3 …
Identification of DNA methylation prognostic signature of acute myelocytic leukemia
H Zhang, G Song, G Song, R Li, M Gao, L Ye… - PLoS One, 2018 - journals.plos.org
Background The aim of this study is to find the potential survival related DNA methylation
signature capable of predicting survival time for acute myelocytic leukemia (AML) patients …
signature capable of predicting survival time for acute myelocytic leukemia (AML) patients …
Profiling of N6-methyladenosine methylation in porcine longissimus dorsi muscle and unravelling the hub gene ADIPOQ promotes adipogenesis in an m6A …
H Gong, T Gong, Y Liu, Y Wang, X Wang - Journal of Animal Science and …, 2023 - Springer
Background Intramuscular fat (IMF) content is a critical indicator of pork quality, and
abnormal IMF is also relevant to human disease as well as aging. Although N6 …
abnormal IMF is also relevant to human disease as well as aging. Although N6 …
Evaluation of leptin and MMP2 genes methylation in childhood obesity
Recent novel eras of research are opening for the effective management of obesity, in
general and childhood obesity, in specific through gene and nutrient intake interactions …
general and childhood obesity, in specific through gene and nutrient intake interactions …