Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
Bioactive natural products in COVID-19 therapy
Z Wang, N Wang, L Yang, X Song - Frontiers in Pharmacology, 2022 - frontiersin.org
The devastating COVID-19 pandemic has caused more than six million deaths worldwide
during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic …
during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic …
The therapeutic potential of natural dietary flavonoids against SARS-CoV-2 infection
Z Wang, L Yang - Nutrients, 2023 - mdpi.com
The exploration of non-toxic and cost-effective dietary components, such as epigallocatechin
3-gallate and myricetin, for health improvement and disease treatment has recently attracted …
3-gallate and myricetin, for health improvement and disease treatment has recently attracted …
An overview of anti-SARS-CoV-2 and anti-inflammatory potential of baicalein and its metabolite baicalin: insights into molecular mechanisms
Abstract The current Coronavirus Disease 2019 (COVID-19) pandemic, caused by the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …
Different aspects of emetine's capabilities as a highly potent SARS-CoV-2 inhibitor against COVID-19
M Valipour - ACS Pharmacology & Translational Science, 2022 - ACS Publications
In the global movement to find the appropriate agents to fight the coronavirus disease of
2019 (COVID-19), emetine is one of the strongest anti-SARS-CoV-2 compounds with sub …
2019 (COVID-19), emetine is one of the strongest anti-SARS-CoV-2 compounds with sub …
Protein-templated ligand discovery via the selection of DNA-encoded dynamic libraries
DNA-encoded chemical libraries (DELs) have become a powerful technology platform in
drug discovery. Dual-pharmacophore DELs display two sets of small molecules at the …
drug discovery. Dual-pharmacophore DELs display two sets of small molecules at the …
[HTML][HTML] Anti-SARS-CoV-2, antioxidant and immunomodulatory potential of dietary flavonol quercetin: Focus on molecular targets and clinical efficacy
The current coronavirus disease 2019 (COVID-19) outbreak, caused by the infection of
SARS-CoV-2, seems to be a tough global challenge because of its highly contagious nature …
SARS-CoV-2, seems to be a tough global challenge because of its highly contagious nature …
Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
The genome of SARS-CoV-2 encodes for a helicase (nsp13) that is essential for viral
replication and highly conserved across related viruses, making it an attractive antiviral …
replication and highly conserved across related viruses, making it an attractive antiviral …
Recent advances in applying G-quadruplex for SARS-CoV-2 targeting and diagnosis: A review
The coronavirus SARS-CoV-2 has caused a health care crisis all over the world since the
end of 2019. Although vaccines and neutralizing antibodies have been developed, rapidly …
end of 2019. Although vaccines and neutralizing antibodies have been developed, rapidly …
[HTML][HTML] Some natural compounds and their analogues having potent anti-SARS-CoV-2 and anti-proteases activities as lead molecules in drug discovery for COVID …
B Dinda, M Dinda, S Dinda, M Chakraborty - European Journal of …, 2022 - Elsevier
Currently an emerging human pathogenic coronavirus, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), caused coronavirus disease 2019 (COVID-19) that has posed …
coronavirus 2 (SARS-CoV-2), caused coronavirus disease 2019 (COVID-19) that has posed …