Proteins are ubiquitous biopolymers that adopt distinct three-dimensional structures and
fulfil a multitude of elementary functions in organisms. Recent systematic studies in …

The human papillomavirus type 16 (HPV-16) E5 protein is a small, hydrophobic polypeptide
that is expressed in virus-infected keratinocytes and alters receptor signaling pathways …

Introduction: Influenza antiviral high-throughput screens have been extensive, and yet no
approved influenza antivirals have been identified through high-throughput screening. This …

The driving forces behind the folding processes of integral membrane proteins after insertion
into the bilayer, is currently under debate. The M2 protein from the influenza A virus is an …

Adamantanamines 16, 18, 21, 24, 27, 28, 30, 32, 35, 36, 37, 40, 46 and 48 were synthesized
and tested for anti-influenza A virus and trypanocidal activity. The stereoelectronic …

The new 2-alkyl-2-aminoadamantanes and analogues 4–10 were designed and
synthesized by simplification of the structure of the potent anti-influenza virus A spiranic …

19F NMR probes were used to follow interactions between ligands in the aminoadamantane
series, amantadine (Am) 1 and 3-F-Am 2, and the 5-F-Trp20 transmembrane fragment of the …

There are two main types of infl uenza viruses, infl uenza A and B, that cause mild to serious
respiratory disease in humans, which is associated with increased deaths every year, and …

Although a typical influenza season poses only a moderate health risk to the general
population, large portions of the community are routinely endangered due to age-related …

36. Catalona WJ, Bartsch G, Rittenhouse HG, Evans CL, Linton HJ, Horninger W, Klocker H,
Mikolajczyk SD, Serum pro-prostate specific antigen preferentially detects aggressive …