Elevated ambient temperatures affect animal production and welfare. Animal's reduced
production performances during heat stress were traditionally thought to result from the …

Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …

Nowadays we understand cell membranes not as a simple double lipid layer but as a
collection of complex and dynamic protein–lipid structures and microdomains that serve as …

Metabolic homeostasis of fatty acids is complex and well-regulated in all organisms. The
biosynthesis of saturated fatty acids (SFA) in mammals provides substrates for β-oxidation …

Heat stress is a common and, therefore, an important environmental impact on cells and
organisms. While much attention has been paid to severe heat stress, moderate temperature …

Neurodegenerative diseases (NDDs) such as Alzheimer's disease, Parkinson's disease and
Huntington's disease (HD), amyotrophic lateral sclerosis, and prion diseases are all …

Beyond guarding the cellular proteome the major stress inducible heat shock protein Hsp70
has been shown to interact with lipids. Non-cytosolic Hsp70 stabilizes membranes during …

Clinical studies have demonstrated the effectiveness of hyperthermia as an adjuvant for
chemotherapy and radiotherapy. However, significant clinical challenges have been …

Since the publication of the fluid mosaic as a relevant model for biological membranes,
accumulating evidence has revealed the outstanding complexity of the composition and …

The classic heat shock (stress) response (HSR) was originally attributed to protein
denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances …