Medicinal plants are the backbone of modern medicine. In recent times, there is a great urge
to discover nootropic medicinal plants to reverse cognitive dysfunction owing to their less …

Neurodegenerative disorders are characterized by the presence of inflammation in areas
with neuronal cell death and a regional increase in iron that exceeds what occurs during …

Identifying early-detection biomarkers have become an increasingly important approach in
the treatment and prevention of Alzheimer's disease (AD). In this study, we investigated the …

Memory deficit is a marker of Alzheimer's disease (AD) that has been highly associated with
the dysfunction of cyclic GMP (cGMP) signaling and an ongoing inflammatory process …

Scientists have worked for over a century to uncover the basis of Alzheimer's disease (AD)
with the ultimate goal of discovering a treatment. However, none of the approaches utilized …

Propofol is a short-acting intra-venous anaesthetic agent and widely used not only in
operating rooms but also in the intensive care unit (ICU). Apart from its multiple anaesthetic …

In this study, we have synthesized and evaluated 18F-JNJ64349311, a tracer with high
affinity for aggregated tau (inhibition constant value, 8 nM) and high (≥ 500×) in vitro …

Alzheimer's disease (AD) is a major problem of health and disability, with a relevant
economic impact on our society. Despite important advances in pathogenesis, diagnosis …

Accumulating evidence displays that an abnormal deposition of amyloid beta-peptide (Aβ) is
the primary cause of the pathogenesis of Alzheimer's disease (AD). And therefore the …

The role of betaine in the liver and kidney has been well documented, even from the cellular
and molecular point of view. Despite literature reporting positive effects of betaine …