The APOBEC family of single-stranded DNA cytosine deaminases comprises a formidable
arm of the vertebrate innate immune system. Pre-vertebrates express a single APOBEC …

Human papillomaviruses (HPVs) are small DNA viruses causally associated with benign
warts and multiple cancers, including cervical and head-and-neck cancers. While the vast …

Summary APOBEC 3 (A3) cytidine deaminases are a family of enzymes that have been
shown to inhibit the replication of HIV‐1 and other retroviruses as part of the innate immune …

Abstract APOBEC3A and APOBEC3G are DNA cytosine deaminases with biological
functions in foreign DNA and retrovirus restriction, respectively. APOBEC3A has an intrinsic …

The human APOBEC3 family consists of seven cytidine deaminases (A3A to A3H), some of
which display potent antiretroviral activity against HIV-1 and other retroviruses. Studies that …

ABSTRACT APOBEC3 (A3) mutation signatures have been observed in a variety of human
cancer genomes, including those of cervical and head and neck cancers caused by human …

The APOBEC3 family of human cytidine deaminases is involved in various cellular
processes, including the innate and acquired immune system, mostly through inducing C-to …

APOBEC3A (A3A), one of the seven-member APOBEC3 family of cytidine deaminases,
lacks strong antiviral activity against lentiviruses but is a potent inhibitor of adeno-associated …

Retroelements comprise a large and successful family of transposable genetic elements
that, through intensive infiltration, have shaped the genomes of humans and other mammals …

ABSTRACT APOBEC enzymes are DNA cytosine deaminases that normally serve as virus
restriction factors, but several members, including APOBEC3H, also contribute to cancer …