Anticoagulation in chronic hemodialysis: progress toward an optimal approach

M Kessler, F Moureau, P Nguyen - Seminars in Dialysis, 2015 - Wiley Online Library
Appropriate anticoagulation for hemodialysis (HD) requires a subtle balance between under‐
and over‐heparinization to prevent extracorporeal circuit (ECC) clotting and bleeding …

Is regional citrate anticoagulation the future of hemodialysis?

J Buturovic‐Ponikvar - Therapeutic Apheresis and Dialysis, 2016 - Wiley Online Library
Citrate has many characteristics of the ideal anticoagulant for hemodialysis. In addition to
immediate and complete anticoagulation in the dialysis circuit, citrate has important effects …

Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis: a prospective multicenter randomized controlled trial

X Tang, D Chen, L Zhang, P Fu, Y Chen, Z Xiao… - Journal of Zhejiang …, 2022 - Springer
Objective Safe and effective anticoagulation is essential for hemodialysis patients who are at
high risk of bleeding. The purpose of this trial is to evaluate the effectiveness and safety of …

Use of regional citrate anticoagulation with medium cut-off membrane: pilot report

MM Vrečko, J Pajek, J Buturović-Ponikvar - BMC nephrology, 2022 - Springer
Background Regional citrate anticoagulation during hemodialysis provides an immediate
and complete anticoagulant effect, which is limited to the extracorporeal circuit. Citrate has …

简化枸橼酸抗凝无肝素透析的疗效观察

朱淑华, 樊蓉, 徐斌 - 肾脏病与透析肾移植杂志, 2017 - njcndt.com
简化枸橼酸抗凝无肝素透析的疗效观察 Page 1 肾脏病与透析肾移植杂志 DOI:10.3969/j.issn.1006⁃298X.2017.04.005
[基金项目] 国家自然科学基金面上项目(81170708);国家重点研发计划课题(2016YFC0904103) …

Modified regional citrate anticoagulation is optimal for hemodialysis in patients at high risk of bleeding: a prospective randomized study of three anticoagulation …

T Lin, L Song, R Huang, Y Huang, S Tang, Q Lin… - BMC nephrology, 2019 - Springer
Background Recommended regular saline flushing presents clinical ineffectiveness for
hemodialysis (HD) patients at high risk of bleeding with heparin contraindication. Regional …

Calcium mass balance during citrate hemodialysis: A randomized controlled trial comparing normal and low ionized calcium target ranges

J Gubensek, A Orsag, R Ponikvar… - PLoS …, 2016 - journals.plos.org
Background Regional citrate anticoagulation (RCA) during hemodialysis interferes with
calcium homeostasis. Optimal ionized calcium (iCa) target range during RCA and …

Citrate anticoagulation for postdilutional online hemodiafiltration with calcium-containing dialysate and infusate: significant clotting in the venous bubble trap

J Buturovic-Ponikvar, J Gubensek… - … journal of artificial …, 2008 - journals.sagepub.com
Background The aim of this prospective clinical study was to assess safety and
antithrombotic efficacy of a regional citrate anticoagulation protocol for postdilutional online …

Treatment efficacy and safety during plasma exchange with citrate anticoagulation: a randomized study of 4 versus 15% citrate

M Antonic, J Gubensek, J Buturovic‐Ponikvar… - Artificial …, 2016 - Wiley Online Library
In plasma exchange (PE), contrary to dialysis, there is no ultrafiltration, and the volume of
anticoagulant contributes to volume overload of the patient and might also reduce PE …

Simplified citrate anticoagulation for CRRT without calcium replacement

M Broman, B Klarin, K SAnDIn, O Carlsson… - Asaio …, 2015 - journals.lww.com
Since 2012, citrate anticoagulation is the recommended anticoagulation strategy for
continuous renal replacement therapy (CRRT). The main drawback using citrate as …