Advancing the global public health agenda for NAFLD: a consensus statement
Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects
approximately one-quarter of the global adult population, causing a substantial burden of ill …
approximately one-quarter of the global adult population, causing a substantial burden of ill …
Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders
J Aron-Wisnewsky, C Vigliotti, J Witjes, P Le… - Nature Reviews …, 2020 - nature.com
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …
Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma
EJ Sun, M Wankell, P Palamuthusingam, C McFarlane… - Biomedicines, 2021 - mdpi.com
Despite advances in the treatment of cancers through surgical procedures and new
pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains challenging as …
pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains challenging as …
Cellular mechanisms of liver fibrosis
The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …
Non-alcoholic steatohepatitis: a review of its mechanism, models and medical treatments
C Peng, AG Stewart, OL Woodman… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic steatohepatitis (NASH) develops from non-alcoholic fatty liver disease
(NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of …
(NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of …
Age as a confounding factor for the accurate non-invasive diagnosis of advanced NAFLD fibrosis
OBJECTIVES: Non-invasive fibrosis scores are widely used to identify/exclude advanced
fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these scores …
fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these scores …
Complete resolution of nonalcoholic fatty liver disease after bariatric surgery: a systematic review and meta-analysis
Background & Aims Bariatric surgery has been reported to lead to complete resolution of
nonalcoholic fatty liver disease (NAFLD) following the sustained weight loss induced in …
nonalcoholic fatty liver disease (NAFLD) following the sustained weight loss induced in …
Defining comprehensive models of care for NAFLD
Non-alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease
globally. Despite the increased demand placed on health-care systems, little attention has …
globally. Despite the increased demand placed on health-care systems, little attention has …
Pathophysiology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
V Manne, P Handa, KV Kowdley - Clinics in liver disease, 2018 - liver.theclinics.com
The pathophysiology of NAFL and NASH is complex and numerous intermediaries are
involved. Each year brings new and exciting developments as pieces of the …
involved. Each year brings new and exciting developments as pieces of the …
Mitochondrial dysfunction plays central role in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …