Sleep is a universal physiological need in all species and is essential for the maintenance
and recovery of various physiological functions of the body. In late years, the gut microbiota …

Trimethylamine lyases are expressed in a wide range of intestinal microbiota which
metabolize dietary nutrients like choline, betaine, and L-carnitine to form trimethylamine …

The relationship between microbiota, short chain fatty acids (SCFAs), and obesity remains
enigmatic. We employ amplicon sequencing and targeted metabolomics in a large (n …

Sleep is essential for our health. Short sleep is known to increase disease risks via
imbalance of intestinal microbiota, dysbiosis. However, mechanisms by which short sleep …

As society ages, the number of patients with spinal degenerative diseases (SDD) is
increasing, posing a major socioeconomic problem for patients and their families. SDD …

Major hallmarks of functional loss, loss of metabolic and musculoskeletal health and (multi)
morbidity with aging are associated with sleep disturbances. With poor sleep shifts in gut …

Background Growing attention is paid to the association between alterations in the gut
microbiota and their metabolites in patients with psychiatric disorders. Our study aimed to …

Bold new approaches are urgently needed to overcome global health challenges. The
proposed Advanced Research Projects Agency for Health (ARPA-H) is intended to provide …

Context Depression is prevalent among Asian Americans (AsA) during the COVID-19
pandemic, and depression often leads to sleep disturbance in this population. The gut …

Cancer incidence is increasing worldwide and is a major cause of mortality. The relative
magnitude of the increase is remarkably high in low human development index (HDI; 95%) …