[HTML][HTML] Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy

R Dong, M Zhang, Q Hu, S Zheng… - International …, 2018 - spandidos-publications.com
Galectin-3 is a member of the galectin family, which are β‑galactoside‑binding lectins with≥
1 evolutionary conserved carbohydrate‑recognition domain. It binds proteins in a …

Personalizing risk stratification for sudden death in dilated cardiomyopathy: the past, present, and future

BP Halliday, JGF Cleland, JJ Goldberger, SK Prasad - Circulation, 2017 - Am Heart Assoc
Results from the DANISH Study (Danish Study to Assess the Efficacy of ICDs in Patients
With Non-Ischemic Systolic Heat Failure on Mortality) suggest that for many patients with …

[HTML][HTML] Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies

S Ravassa, B López, TA Treibel, G San José… - Molecular Aspects of …, 2023 - Elsevier
Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …

Galectin-3 in heart failure: an update of the last 3 years

C Gehlken, N Suthahar, WC Meijers… - Heart failure …, 2018 - heartfailure.theclinics.com
This article provides an update regarding the most recent published literature on galectin-3
as a biomarker in heart failure (HF) and gives an outlook toward its use as a biotarget. 1 In …

Catecholamine-induced cardiotoxicity: a critical element in the pathophysiology of stroke-induced heart injury

Y Du, LJ Demillard, J Ren - Life Sciences, 2021 - Elsevier
Cerebrovascular diseases such as ischemic stroke, brain hemorrhage, and subarachnoid
hemorrhage provoke cardiac complications such as heart failure, neurogenic stress-related …

Non-ischemic dilated cardiomyopathy and cardiac fibrosis

BO Cojan-Minzat, A Zlibut, L Agoston-Coldea - Heart Failure Reviews, 2021 - Springer
Cardiac fibrosis is associated with non-ischemic dilated cardiomyopathy, increasing its
morbidity and mortality. Cardiac fibroblast is the keystone of fibrogenesis, being activated by …

[HTML][HTML] The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases

G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

The role of galectin‐3 in heart failure and cardiovascular disease

X Zhong, X Qian, G Chen… - Clinical and Experimental …, 2019 - Wiley Online Library
Summary Galectin‐3, a β‐galactoside‐binding lectin, is a new important player in the
progression of heart failure (HF) and is also linked to poor outcome in patients with …

Meta-analysis of the usefulness of plasma galectin-3 to predict the risk of mortality in patients with heart failure and in the general population

TF Imran, HJ Shin, N Mathenge, F Wang, B Kim… - The American journal of …, 2017 - Elsevier
Galectin-3 is an emerging biomarker of myocardial fibrosis, inflammation, and immune
response. We sought to examine the relation of plasma galectin-3 with cardiovascular (CVD) …

[HTML][HTML] Roles of biomarkers in myocardial fibrosis

Y Ding, Y Wang, W Zhang, Q Jia, X Wang, Y Li… - Aging and …, 2020 - ncbi.nlm.nih.gov
Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in
the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the …