Evolution and roles of stanniocalcin

BHY Yeung, AYS Law, CKC Wong - Molecular and cellular endocrinology, 2012 - Elsevier
In fish, stanniocalcin-1 (STC1) is a key endocrine factor that acts on gill, intestine and kidney
to regulate serum calcium and phosphate homeostasis. The recent identification and study …

Macrophages in vascular inflammation–from atherosclerosis to vasculitis

T Shirai, M Hilhorst, DG Harrison, JJ Goronzy… - …, 2015 - Taylor & Francis
The spectrum of vascular inflammatory disease ranges from atherosclerosis and
hypertension, widespread conditions affecting large proportions of the population, to the …

Genome-wide association identifies diverse causes of common variable immunodeficiency

JS Orange, JT Glessner, E Resnick, KE Sullivan… - Journal of allergy and …, 2011 - Elsevier
Background Common variable immunodeficiency (CVID) is a heterogeneous immune defect
characterized by hypogammaglobulinemia, failure of specific antibody production …

“A rose is a rose is a rose,” but CVID is not CVID: common variable immune deficiency (CVID), what do we know in 2011?

PFK Yong, JED Thaventhiran, B Grimbacher - Advances in immunology, 2011 - Elsevier
Common variable immune deficiency (CVID) is the commonest symptomatic primary
immunodeficiency and represents a heterogenous collection of disorders resulting mostly in …

Preconditioning enhances the paracrine effect of mesenchymal stem cells in preventing oxygen-induced neonatal lung injury in rats

P Waszak, R Alphonse, A Vadivel… - Stem cells and …, 2012 - liebertpub.com
Bronchopulmonary dysplasia (BPD) remains a main complication of extreme prematurity.
Bone marrow derived-mesenchymal stem cells (BM-MSC) prevent lung injury in an O2 …

Subendothelial stiffness alters endothelial cell traction force generation while exerting a minimal effect on the transcriptome

EE Bastounis, YT Yeh, JA Theriot - Scientific reports, 2019 - nature.com
Endothelial cells respond to changes in subendothelial stiffness by altering their migration
and mechanics, but whether those responses are due to transcriptional reprogramming …

STC1 expression is associated with tumor growth and metastasis in breast cancer

ACM Chang, J Doherty, LI Huschtscha… - Clinical & experimental …, 2015 - Springer
Abstract Stanniocalcin-1 (STC1) is a secreted glycoprotein implicated in several pathologies
including retinal degeneration, cerebral ischemia, angiogenesis and inflammation. Aberrant …

Mesenchymal stem cells correct inappropriate epithelial–mesenchyme relation in pulmonary fibrosis using stanniocalcin-1

M Ono, S Ohkouchi, M Kanehira, N Tode… - Molecular Therapy, 2015 - cell.com
Current hypotheses suggest that aberrant wound healing has a critical role in the
pathogenesis of idiopathic pulmonary fibrosis (IPF). In these hypotheses, continuous TGF-β1 …

Mesenchymal stromal cells protect cancer cells from ROS-induced apoptosis and enhance the Warburg effect by secreting STC1

S Ohkouchi, GJ Block, AM Katsha, M Kanehira… - Molecular Therapy, 2012 - cell.com
Previous studies have demonstrated that mesenchymal stromal cells (MSCs) enhance cell
survival through upregulation and secretion of stanniocalcin-1 (STC1). This study shows that …

[HTML][HTML] Endothelial cell dysfunction in hyperglycemia: Phenotypic change, intracellular signaling modification, ultrastructural alteration, and potential clinical …

D Popov - International Journal of Diabetes Mellitus, 2010 - Elsevier
Hyperglycemia, the hallmark of Diabetes mellitus, is a major risk factor for endothelial
dysfunction and vascular complication. In recent years, significant achievements have been …