The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …

Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for
decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It …

It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …

Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …

It is well established that muscle contractions during exercise lead to elevated levels of
reactive oxygen species (ROS) in skeletal muscle. These highly reactive molecules have …

Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

The first suggestion that physical exercise results in free radical-mediated damage to tissues
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …

Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and
contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide …