Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …

Despite concerted clinical and research efforts, cancer is a leading cause of death
worldwide. Surgery, radiation, and chemotherapy have remained the most common …

Long-term survival rates in childhood acute lymphoblastic leukemia (ALL) are currently
above 85% due to huge improvements in treatment. However, 15-20% of children still …

Cancer stem cells are increasingly becoming a primary target for new cancer treatment
development. The ability to study their transient behavior in vitro will provide the opportunity …

The expression, localization, and function of connexins, the protein subunits that comprise
gap junctions, are often altered in cancer. In addition to cell–cell coupling through gap …

Cell adhesion is a process through which cells interact with and attach to neighboring cells
or matrix using specialized surface cell adhesion molecules (AMs). Adhesion plays an …

Extracellular vesicle (EV) trafficking provides for a constitutive mode of cell-cell
communication within tissues and between organ systems. Different EV subtypes have been …

The bone marrow (BM) niche impacts the progression of acute myeloid leukemia (AML) by
favoring the chemoresistance of AML cells. Intimate interactions between leukemic cells and …

Gap-junction-mediated cell-cell communication enables tumor cells to synchronize complex
processes. We previously found that glioblastoma cancer stem cells (CSCs) express higher …

The crosstalk between hematopoietic stem cells (HSC) and bone marrow (BM)
microenvironment is critical for homeostasis and hematopoietic regeneration in response to …