Age-associated physiological and pathological changes at the blood–brain barrier: A review
F Erdő, L Denes, E de Lange - Journal of Cerebral Blood …, 2017 - journals.sagepub.com
The age-associated decline of the neurological and cognitive functions becomes more and
more serious challenge for the developed countries with the increasing number of aged …
more serious challenge for the developed countries with the increasing number of aged …
Blood–brain barrier dysfunction, seizures and epilepsy
EA Van Vliet, E Aronica, JA Gorter - Seminars in cell & Developmental …, 2015 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex system which separates the brain
from the blood. It helps to maintain the homeostasis of the brain, which is essential for …
from the blood. It helps to maintain the homeostasis of the brain, which is essential for …
Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction
I Weissberg, L Wood, L Kamintsky, O Vazquez… - Neurobiology of …, 2015 - Elsevier
Post-injury epilepsy (PIE) is a common complication following brain insults, including
ischemic, and traumatic brain injuries. At present, there are no means to identify the patients …
ischemic, and traumatic brain injuries. At present, there are no means to identify the patients …
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis
RL Williams-Karnesky, US Sandau… - The Journal of …, 2013 - Am Soc Clin Investig
Epigenetic modifications, including changes in DNA methylation, lead to altered gene
expression and thus may underlie epileptogenesis via induction of permanent changes in …
expression and thus may underlie epileptogenesis via induction of permanent changes in …
Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms
F Alyu, M Dikmen - Acta neuropsychiatrica, 2017 - cambridge.org
ObjectiveEpilepsy is a chronic neurological disease characterised with seizures. The
aetiology of the most generalised epilepsies cannot be explicitly determined and the …
aetiology of the most generalised epilepsies cannot be explicitly determined and the …
Status epilepticus, blood–brain barrier disruption, inflammation, and epileptogenesis
JA Gorter, EA van Vliet, E Aronica - Epilepsy & Behavior, 2015 - Elsevier
Over the last 15 years, attention has been focused on dysfunction of the cerebral vasculature
and inflammation as important players in epileptogenic processes, with a specific emphasis …
and inflammation as important players in epileptogenic processes, with a specific emphasis …
Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis
X Dong, J Fan, D Lin, X Wang, H Kuang, L Gong… - Journal of …, 2022 - Springer
Evidence from experimental and clinical studies implicates immuno-inflammatory responses
as playing an important role in epilepsy-induced brain injury. Captopril, an angiotensin …
as playing an important role in epilepsy-induced brain injury. Captopril, an angiotensin …
Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview
The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …
Assessment of permeability in barrier type of endothelium in brain using tracers: Evans blue, sodium fluorescein, and horseradish peroxidase
M Kaya, B Ahishali - Permeability barrier: methods and protocols, 2011 - Springer
Blood–brain barrier (BBB) constituted primarily by the capillary endothelial cells functions to
maintain a constant environment for the brain, by preventing or slowing down the passage of …
maintain a constant environment for the brain, by preventing or slowing down the passage of …
Epileptiform activity induces vascular remodeling and zonula occludens 1 downregulation in organotypic hippocampal cultures: role of VEGF signaling pathways
M Morin-Brureau, A Lebrun, MC Rousset… - Journal of …, 2011 - Soc Neuroscience
Recent studies suggest that blood–brain barrier (BBB) permeability contributes to
epileptogenesis in symptomatic epilepsies. We have previously described angiogenesis …
epileptogenesis in symptomatic epilepsies. We have previously described angiogenesis …