[HTML][HTML] Ex vivo lung perfusion

T Watanabe, M Cypel, S Keshavjee - Journal of thoracic disease, 2021 - ncbi.nlm.nih.gov
Lung transplantation is a life-saving treatment for patients with end stage lung disease. The
imbalance between lung graft supply and recipients has been a serious issue and barrier to …

Primary graft dysfunction (PGD) following lung transplantation

RJ Shah, JM Diamond - Seminars in respiratory and critical …, 2018 - thieme-connect.com
Primary graft dysfunction (PGD) is a form of acute lung injury that results from ischemia
reperfusion injury (IRI) and is the major cause of early posttransplant morbidity and mortality …

Postoperative management of lung transplant recipients in the intensive care unit

M Di Nardo, J Tikkanen, S Husain, LG Singer… - …, 2022 - pubs.asahq.org
The number of lung transplantations is progressively increasing worldwide, providing new
challenges to interprofessional teams and the intensive care units. The outcome of lung …

[HTML][HTML] Necrostatin-1 alleviates lung ischemia-reperfusion injury via inhibiting necroptosis and apoptosis of lung epithelial cells

L Dong, F Liang, Z Lou, Y Li, J Li, Y Chen, J Ding… - Cells, 2022 - mdpi.com
Lung ischemia-reperfusion injury (LIRI) is associated with many diseases, including primary
graft dysfunction after lung transplantation, and has no specific and effective therapies …

International consensus recommendations for anesthetic and intensive care management of lung transplantation. An EACTAIC, SCA, ISHLT, ESOT, ESTS, and AST …

N Marczin, EEC de Waal, PMA Hopkins… - The Journal of Heart …, 2021 - jhltonline.org
From the aHarefield Hospital Royal Brompton and Harefield Hospitals, Imperial College
London, London, United Kingdom, Semmelweis University, Budapest, Hungary; bUniversity …

[HTML][HTML] Mitochondrial transplant after ischemia reperfusion promotes cellular salvage and improves lung function during ex-vivo lung perfusion

CM Cloer, CS Givens, LK Buie, LK Rochelle… - The Journal of Heart and …, 2023 - Elsevier
Background In lung transplantation, ischemia-reperfusion injury associated with
mitochondrial damage can lead to graft rejection. Intact, exogenous mitochondria provide a …

Prolonged cold ischemia induces necroptotic cell death in ischemia–reperfusion injury and contributes to primary graft dysfunction after lung transplantation

X Wang, ME O'Brien, J Yu, C Xu, Q Zhang… - American journal of …, 2019 - atsjournals.org
Primary graft dysfunction (PGD) is a major cause of morbidity and mortality after lung
transplantation. Ischemia–reperfusion injury (IRI) is a key event that contributes to PGD …

[HTML][HTML] Effect of targeted coagulopathy management and 5% albumin as volume replacement therapy during lung transplantation on allograft function: a secondary …

J Vajter, J Vachtenheim Jr, Z Prikrylova… - BMC Pulmonary …, 2023 - Springer
Background Primary graft dysfunction (PGD) after lung transplantation (LuTx) contributes
substantially to early postoperative morbidity. Both intraoperative transfusion of a large …

Lung transplantation in pulmonary sarcoidosis

JS Kim, R Gupta - Journal of Autoimmunity, 2023 - Elsevier
Sarcoidosis is a systemic inflammatory disease of unknown etiology and variable clinical
course. Pulmonary sarcoidosis is the most common presentation and accounts for most …

Liproxstatin-1 Alleviates Lung Transplantation-induced Cold Ischemia–Reperfusion Injury by Inhibiting Ferroptosis

J Zhao, J Li, D Wei, F Gao, X Yang, B Yue… - …, 2023 - journals.lww.com
Background. Primary graft dysfunction, which is directly related to cold ischemia–reperfusion
(CI/R) injury, is a major obstacle in lung transplantation (LTx). Ferroptosis, a novel mode of …