Potential therapeutic uses of BDNF in neurological and psychiatric disorders
AH Nagahara, MH Tuszynski - Nature reviews Drug discovery, 2011 - nature.com
The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
Neurotrophin signalling in the human nervous system
S Ateaque, S Merkouris, YA Barde - Frontiers in molecular …, 2023 - frontiersin.org
This review focuses on neurotrophins and their tyrosine kinase receptors, with an emphasis
on their relevance to the function and dysfunction in the human nervous system. It also deals …
on their relevance to the function and dysfunction in the human nervous system. It also deals …
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons
S Dieni, T Matsumoto, M Dekkers, S Rauskolb… - Journal of Cell …, 2012 - rupress.org
Although brain-derived neurotrophic factor (BDNF) regulates numerous and complex
biological processes including memory retention, its extremely low levels in the mature …
biological processes including memory retention, its extremely low levels in the mature …
Impact of brain‐derived neurotrophic factor genetic polymorphism on cognition: A systematic review
YL Toh, T Ng, M Tan, A Tan, A Chan - Brain and behavior, 2018 - Wiley Online Library
Introduction Brain‐derived neurotrophic factor (BDNF) has an important role in the
neurogenesis and neuroplasticity of the brain. This systematic review was designed to …
neurogenesis and neuroplasticity of the brain. This systematic review was designed to …
BDNF Val66Met and cognition: all, none, or some? A meta‐analysis of the genetic association
SD Mandelman, EL Grigorenko - Genes, Brain and Behavior, 2012 - Wiley Online Library
The Val66Met, G196A (rs6265) polymorphism in the brain‐derived neurotrophic factor gene,
BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet …
BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet …
Effect of BDNF val66met polymorphism on declarative memory and its neural substrate: A meta-analysis
JP Kambeitz, S Bhattacharyya… - Neuroscience & …, 2012 - Elsevier
Brain derived neurotrophic factor (BDNF) is a critical component of the molecular
mechanism of memory formation. Variation in the BDNF gene, particularly the rs6265 …
mechanism of memory formation. Variation in the BDNF gene, particularly the rs6265 …
The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, promotes
survival and synaptic plasticity in the human brain. The Val66Met polymorphism of the BDNF …
survival and synaptic plasticity in the human brain. The Val66Met polymorphism of the BDNF …
Levels of brain‐derived neurotrophic factor in patients with multiple sclerosis
Y Naegelin, K Saeuberli, S Schaedelin… - Annals of clinical …, 2020 - Wiley Online Library
Objective To determine the levels of brain‐derived neurotrophic factor (BDNF) in the serum
of patients suffering from multiple sclerosis (MS) to evaluate the potential of serum BDNF as …
of patients suffering from multiple sclerosis (MS) to evaluate the potential of serum BDNF as …
BDNF polymorphism predicts the rate of decline in skilled task performance and hippocampal volume in healthy individuals
MM Sanchez, D Das, JL Taylor, A Noda… - Translational …, 2011 - nature.com
Numerous studies have indicated a link between the presence of polymorphism in brain-
derived neurotrophic factor (BDNF) and cognitive and affective disorders. However, only a …
derived neurotrophic factor (BDNF) and cognitive and affective disorders. However, only a …
KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden
A single nucleotide polymorphism, rs17070145, in the KIdney and BRAin expressed protein
(KIBRA) gene has been associated with cognition and hippocampal volume in cognitively …
(KIBRA) gene has been associated with cognition and hippocampal volume in cognitively …