Antioxidant, anti-inflammatory, and immunomodulatory roles of nonvitamin antioxidants in anti-SARS-CoV-2 therapy

AM Pisoschi, F Iordache, L Stanca… - Journal of Medicinal …, 2022 - ACS Publications
Viral pathologies encompass activation of pro-oxidative pathways and inflammatory burst.
Alleviating overproduction of reactive oxygen species and cytokine storm in COVID-19 is …

Mitochondrial glutathione in cellular redox homeostasis and disease manifestation

TH Chen, HC Wang, CJ Chang, SY Lee - International Journal of …, 2024 - mdpi.com
Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …

Elevating the discourse on drug delivery: A fresh perspective on the utilization of coordination chemistry-driven metal-drug conjugates

M Biswas, KK Choudhury, A Banerjee… - Coordination Chemistry …, 2024 - Elsevier
The drug development paradigm needed a significant shift towards utilizing bio-compatible
metal ions to stabilize potent drugs and enable their stimuli-responsive release. Highly …

Effect of Bis (maltolato) oxovanadium (IV) on zinc, copper, and manganese homeostasis and DMT1 mRNA expression in streptozotocin-induced hyperglycemic rats

C Sánchez-González, L Moreno, P Aranda… - Biology, 2022 - mdpi.com
Simple Summary Diabetes mellitus is a disease that affects some metabolic processes,
altering the metabolism of trace elements associated with the antioxidant defense system …

The arsenic-lowering effect of inulin-type prebiotics in end-stage renal disease: a randomized crossover trial

L Li, J Zhao, J Wang, Q Xiong, X Lin, X Guo, F Peng… - Food & Function, 2024 - pubs.rsc.org
Background: Circulatory imbalance of trace elements is frequent in end-stage renal disease
(ESRD), leading to a deficiency of essential elements and excess of toxic elements. The …

Imbalanced and Unchecked: The Role of Metal Dyshomeostasis in Driving COPD Progression

Y Cui, X Du, Y Li, D Wang, Z Lv, H Yuan… - COPD: Journal of …, 2024 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition
characterized by persistent inflammation and oxidative stress, which ultimately leads to …

Effect of zinc supplementation on glycemic biomarkers: an umbrella of interventional meta-analyses

M Daneshvar, M Ghaheri, D Safarzadeh… - Diabetology & Metabolic …, 2024 - Springer
Background Several studies have evaluated the effects of zinc supplementation on glycemic
biomarkers in humans and have demonstrated varying results. We systematically evaluated …

[HTML][HTML] Молекулярные механизмы, определяющие применение комбинации глицина и цинка в коррекции основных проявлений стресса и тревоги

ВН Шишкова, ЯР Нарциссов, ВЮ Титова… - Фармация и …, 2022 - cyberleninka.ru
Цель. Работа посвящена системному анализу молекулярных механизмов,
определяющих возможность комбинированного использования аминокислоты глицин и …

Zinc and Chronic Kidney Disease: A Review

W Chen, H Lu, Y Ying, H Li, H Shen… - Journal of Nutritional …, 2024 - jstage.jst.go.jp
Chronic kidney disease (CKD) poses a major global public health challenge. The World
Health Organization's data shows that CKD affects about 10% of the world's population …

Protective role of zinc oxide nanoparticles in alleviating flumethrin-induced hepatic and renal toxicity in male albino rats

AK Fayeq, FI Abo El-Ela, NS Shaban, AM Radi… - Toxicology and …, 2023 - Springer
Abstract Objectives Zinc oxide nanoparticles (ZnO-NPs) are now well known as antioxidants
that have been linked to a relief of oxidative stress induced by several xenobiotics. The …