The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases

G Műzes, F Sipos - Cells, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …

Immunomodulatory properties of mesenchymal stromal cells: an update

L Müller, A Tunger, M Wobus, M von Bonin… - Frontiers in cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to
modulate the phenotype and functional properties of various immune cells that play an …

Comparison of immunotherapy mediated by apoptotic bodies, microvesicles and exosomes: apoptotic bodies' unique anti-inflammatory potential

J Wen, D Creaven, X Luan, J Wang - Journal of Translational Medicine, 2023 - Springer
Immunotherapy, including immunostimulation and immunosuppression, has seen significant
development in the last 10 years. Immunostimulation has been verified as effective in anti …

Distinct mechanisms mediating therapy-induced cellular senescence in prostate cancer

J Kallenbach, G Atri Roozbahani, M Heidari Horestani… - Cell & Bioscience, 2022 - Springer
Abstract Background Prostate cancer (PCa) is an age-related malignancy in men with a high
incidence rate. PCa treatments face many obstacles due to cancer cell resistance and many …

Immunomodulatory effect of MSCs and MSCs-derived extracellular vesicles in systemic lupus erythematosus

C Yang, J Sun, Y Tian, H Li, L Zhang, J Yang… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a common autoimmune connective tissue disease
with unclear etiology and pathogenesis. Mesenchymal stem cell (MSC) and MSC derived …

Immunomodulatory effects of umbilical mesenchymal stem cell-derived exosomes on CD4+ T cells in patients with primary Sjögren's syndrome

D Ma, Z Wu, X Zhao, X Zhu, Q An, Y Wang, J Zhao… - …, 2023 - Springer
Abstract Background Primary Sjögren's syndrome (pSS) is an autoimmune disease that
leads to the destruction of exocrine glands and multisystem lesions. Abnormal proliferation …

Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation

MR Mohammadi, SM Rodriguez, JC Luong, S Li… - Communications …, 2021 - nature.com
Foreign body response (FBR) to biomaterials compromises the function of implants and
leads to medical complications. Here, we report a hybrid alginate microcapsule (AlgXO) that …

Knowledge mapping of exosomes in autoimmune diseases: a bibliometric analysis (2002–2021)

F Wu, J Gao, J Kang, X Wang, Q Niu, J Liu… - Frontiers in …, 2022 - frontiersin.org
Background Autoimmune diseases (AIDs) are a class of chronic disabling diseases
characterized by inflammation and damage to muscles, joints, bones, and internal organs …

The latest developments in immunomodulation of mesenchymal stem cells in the treatment of intrauterine adhesions, both allogeneic and autologous

J Chen, Q Huang, Y Zhao, W Chen, S Lin… - Frontiers in …, 2021 - frontiersin.org
Intrauterine adhesion (IUA) is an endometrial fibrosis disease caused by repeated
operations of the uterus and is a common cause of female infertility. In recent years …