Lipid vesicles: A versatile drug delivery platform for dermal and transdermal applications

IA Chacko, VM Ghate, L Dsouza, SA Lewis - Colloids and Surfaces B …, 2020 - Elsevier
Topical and transdermal application of active pharmaceutical ingredients to the skin is an
attractive strategy being explored by formulation scientists to treat disease conditions rather …

The technology of transdermal delivery nanosystems: from design and development to preclinical studies

D Despotopoulou, N Lagopati, S Pispas… - International Journal of …, 2022 - Elsevier
Transdermal administration has gained much attention due to the remarkable advantages
such as patient compliance, drug escape from first-pass elimination, favorable …

[HTML][HTML] Surface-modified bilosomes nanogel bearing a natural plant alkaloid for safe management of rheumatoid arthritis inflammation

MH Elkomy, NK Alruwaili, M Elmowafy, K Shalaby… - Pharmaceutics, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The
characteristic of RA is gradual joint deterioration. Current RA treatment alleviates signs such …

Development of acetazolamide loaded bilosomes for improved ocular delivery: Preparation, characterization and in vivo evaluation

AM Mohsen, A Salama, AA Kassem - Journal of Drug Delivery Science and …, 2020 - Elsevier
Acetazolamide (ACZ), a carbonic anhydrase inhibitor, is employed to decrease the
intraocular pressure (IOP) in glaucoma patients. ACZ is characterized by low aqueous …

Unique green chromatography method for the determination of serotonin receptor antagonist (Ondansetron hydrochloride) related substances in a liquid formulation …

LP Kowtharapu, NK Katari, CA Sandoval… - Journal of …, 2022 - Wiley Online Library
Serotonin receptor antagonist drug Ondansetron hydrochloride injectable formulation
containing all related substances was identified and quantified by a single, simple, sensitive …

[HTML][HTML] Tailoring of novel bile salt stabilized vesicles for enhanced transdermal delivery of simvastatin: a new therapeutic approach against inflammation

ES Khafagy, BK Almutairy, AS Abu Lila - Polymers, 2023 - mdpi.com
Simvastatin (SMV), a cholesterol-lowering agent, has antioxidant and anti-inflammatory
effects. Nevertheless, the oral use of SMV is linked with poor systemic bioavailability owing …

[HTML][HTML] Formulation of miconazole-loaded chitosan–carbopol vesicular gel: optimization to in vitro characterization, irritation, and antifungal assessment

SS Imam, SJ Gilani, A Zafar, MNB Jumah, S Alshehri - Pharmaceutics, 2023 - mdpi.com
Miconazole nitrate (MN) is a poorly water-soluble and antifungal drug used for fungal
infections. The present research work was designed to develop topical MN-loaded …

TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells

H Hegazy, MM Amin, W Fayad, MY Zakaria - International Journal of …, 2022 - Elsevier
The goal of this work was to design nude bilosomes (Bil) and D-alpha-tocopheryl
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …

[HTML][HTML] Formulation and evaluation of moxifloxacin loaded bilosomes in-situ gel: optimization to antibacterial evaluation

A Zafar, OA Alsaidan, SS Imam, M Yasir, KS Alharbi… - Gels, 2022 - mdpi.com
In this study, moxifloxacin (MX)-loaded bilosome (BS) in situ gel was prepared to improve
ocular residence time. MX-BSs were prepared using the thin-film hydration method. They …

[HTML][HTML] Novel bile salt stabilized vesicles-mediated effective topical delivery of diclofenac sodium: A new therapeutic approach for pain and inflammation

TM Mahmoud, MM Nafady, HO Farouk, DM Mahmoud… - Pharmaceuticals, 2022 - mdpi.com
The oral delivery of diclofenac sodium (DNa), a non-steroidal analgesic, anti-inflammatory
drug, is associated with various gastrointestinal side effects. The aim of the research was to …