[HTML][HTML] Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …

Sensory perception in autism

CE Robertson, S Baron-Cohen - Nature Reviews Neuroscience, 2017 - nature.com
Autism is a complex neurodevelopmental condition, and little is known about its
neurobiology. Much of autism research has focused on the social, communication and …

[HTML][HTML] Trastorno del espectro autista (TEA)

GC Alcalá, MG Ochoa Madrigal - Revista de la Facultad de Medicina …, 2022 - scielo.org.mx
El trastorno del espectro autista (TEA) es una afección del desarrollo neurológico con
implicación multidimensional, caracterizada por una interacción social disminuida con …

[HTML][HTML] Reduced GABAergic action in the autistic brain

CE Robertson, EM Ratai, N Kanwisher - Current Biology, 2016 - cell.com
An imbalance between excitatory/inhibitory neurotransmission has been posited as a central
characteristic of the neurobiology of autism [1], inspired in part by the striking prevalence of …

[HTML][HTML] Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex

H Sacai, K Sakoori, K Konno, K Nagahama… - Nature …, 2020 - nature.com
Autism spectrum disorder (ASD) is thought to result from deviation from normal development
of neural circuits and synaptic function. Many genes with mutation in ASD patients have …

Restricted and repetitive behaviors in autism spectrum disorders: a review of research in the last decade.

SR Leekam, MR Prior, M Uljarevic - Psychological bulletin, 2011 - psycnet.apa.org
Restricted and repetitive behaviors (RRBs) are a core feature of autism spectrum disorders.
They constitute a major barrier to learning and social adaptation, but research on their …

Model of autism: increased ratio of excitation/inhibition in key neural systems

JLR Rubenstein, MM Merzenich - Genes, Brain and Behavior, 2003 - Wiley Online Library
Autism is a severe neurobehavioral syndrome, arising largely as an inherited disorder,
which can arise from several diseases. Despite recent advances in identifying some genes …

[PDF][PDF] Systematic review of tools to measure outcomes for young children with autism spectrum disorder

H McConachie, JR Parr, M Glod, J Hanratty… - 2015 - ore.exeter.ac.uk
BACKGROUND: The needs of children with autism spectrum disorder (ASD) are complex
and this is reflected in the number and diversity of outcomes assessed and measurement …

GABA system dysfunction in autism and related disorders: from synapse to symptoms

S Coghlan, J Horder, B Inkster, MA Mendez… - Neuroscience & …, 2012 - Elsevier
Autism spectrum disorders (ASDs) are neurodevelopmental syndromes characterised by
repetitive behaviours and restricted interests, impairments in social behaviour and relations …

The genetics of autism

R Muhle, SV Trentacoste, I Rapin - Pediatrics, 2004 - publications.aap.org
Autism is a complex, behaviorally defined, static disorder of the immature brain that is of
great concern to the practicing pediatrician because of an astonishing 556% reported …