Multiplexed imaging in oncology
In oncology, technologies for clinical molecular imaging are used to diagnose patients,
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …
Targeted radionuclide therapy of prostate cancer—from basic research to clinical perspectives
M Czerwińska, A Bilewicz, M Kruszewski… - Molecules, 2020 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men and the second
leading cause of cancer-related deaths in Western civilization. Although localized prostate …
leading cause of cancer-related deaths in Western civilization. Although localized prostate …
De novo approaches to the solid-phase separation of Titanium (IV) and Scandium (III): translating speciation data to selective on-bead chelation toward applications in …
AJ Koller, L Wang, M Deluca, O Glaser… - Inorganic …, 2023 - ACS Publications
The solution chemistry of the hydrolytic, early-transition-metal ions Ti4+ and Sc3+ represents
a coordination chemistry challenge with important real-world implications, specifically in the …
a coordination chemistry challenge with important real-world implications, specifically in the …
Design strategies and medicinal applications of metal-peptidic bioconjugates
SM Meier-Menches, A Casini - Bioconjugate Chemistry, 2020 - ACS Publications
The conjugation of metal-based scaffolds to peptides, proteins, or antibodies allows the
systemic targeting of these payloads to specific locations in the body, such as target …
systemic targeting of these payloads to specific locations in the body, such as target …
[HTML][HTML] Advances in surface enhanced Raman spectroscopy for in vivo imaging in oncology
In the last two decades, the application of surface enhanced Raman scattering (SERS)
nanoparticles for preclinical cancer imaging has attracted increasing attention. Raman …
nanoparticles for preclinical cancer imaging has attracted increasing attention. Raman …
Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis
A major limitation of immunotherapy is the development of resistance resulting from cancer-
mediated inhibition of host lymphocytes. Cancer cells release CCL2 to recruit classical …
mediated inhibition of host lymphocytes. Cancer cells release CCL2 to recruit classical …
Atomic nanogenerators in targeted alpha therapies: Curie's legacy in modern cancer management
M Roscher, G Bakos, M Benešová - Pharmaceuticals, 2020 - mdpi.com
Atomic in vivo nanogenerators such as actinium-225, thorium-227, and radium-223 are of
increasing interest and importance in the treatment of patients with metastatic cancer …
increasing interest and importance in the treatment of patients with metastatic cancer …
Implementing Ac-225 labelled radiopharmaceuticals: practical considerations and (pre-) clinical perspectives
EL Hooijman, V Radchenko, SW Ling… - EJNMMI …, 2024 - Springer
Background In the past years, there has been a notable increase in interest regarding
targeted alpha therapy using Ac-225, driven by the observed promising clinical anti-tumor …
targeted alpha therapy using Ac-225, driven by the observed promising clinical anti-tumor …
Recent advances and impending challenges for the radiopharmaceutical sciences in oncology
This paper is the first of a Series on theranostics that summarises the current landscape of
the radiopharmaceutical sciences as they pertain to oncology. In this Series paper, we …
the radiopharmaceutical sciences as they pertain to oncology. In this Series paper, we …
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy
CN Funeh, J Bridoux, T Ertveldt, TWM De Groof… - Pharmaceutics, 2023 - mdpi.com
The precise delivery of cytotoxic radiation to cancer cells through the combination of a
specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has …
specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has …