A brief history of IL-9
IL-9 was first described in the late 1980s as a member of a growing number of cytokines that
had pleiotropic functions in the immune system. Although many biological functions have …
had pleiotropic functions in the immune system. Although many biological functions have …
Protective and harmful immunity to RSV infection
Respiratory syncytial virus (RSV) is an exceptional mucosal pathogen. It specializes in
infection of the ciliated respiratory epithelium, causing disease of variable severity with little …
infection of the ciliated respiratory epithelium, causing disease of variable severity with little …
[HTML][HTML] IL-9 aggravates SARS-CoV-2 infection and exacerbates associated airway inflammation
SARS-CoV-2 infection is known for causing broncho-alveolar inflammation. Interleukin 9 (IL-
9) induces airway inflammation and bronchial hyper responsiveness in respiratory viral …
9) induces airway inflammation and bronchial hyper responsiveness in respiratory viral …
TH9 cells are required for tissue mast cell accumulation during allergic inflammation
S Sehra, W Yao, ET Nguyen, NL Glosson-Byers… - Journal of Allergy and …, 2015 - Elsevier
Background IL-9 is important for the growth and survival of mast cells. IL-9 is produced by T
cells, natural killer T cells, mast cells, eosinophils, and innate lymphoid cells, although the …
cells, natural killer T cells, mast cells, eosinophils, and innate lymphoid cells, although the …
[HTML][HTML] Th9 cells drive host immunity against gastrointestinal worm infection
P Licona-Limón, J Henao-Mejia, AU Temann… - Immunity, 2013 - cell.com
Type 2 inflammatory cytokines, including interleukin-4 (IL-4), IL-5, IL-9, and IL-13, drive the
characteristic features of immunity against parasitic worms and allergens. Whether IL-9 …
characteristic features of immunity against parasitic worms and allergens. Whether IL-9 …
[HTML][HTML] Clinical aspects and cytokine response in severe H1N1 influenza A virus infection
N Hagau, A Slavcovici, DN Gonganau, S Oltean… - Critical care, 2010 - Springer
Introduction The immune responses in patients with novel A (H1N1) virus infection (nvA
(H1N1)) are incompletely characterized. We investigated the profile of Th1 and Th17 …
(H1N1)) are incompletely characterized. We investigated the profile of Th1 and Th17 …
From interleukin‐9 to T helper 9 cells
M Stassen, E Schmitt, T Bopp - … of the New York Academy of …, 2012 - Wiley Online Library
Interleukin‐9 (IL‐9), cloned more than 20 years ago, was initially thought to be a Th2‐
specific cytokine. This assumption was initially confirmed by functional analyses showing …
specific cytokine. This assumption was initially confirmed by functional analyses showing …
The Important Role of Interleukin‐2 in COVID‐19
L Ghanbari Naeini, L Abbasi, F Karimi… - Journal of …, 2023 - Wiley Online Library
There is controversial literature about the effects of the interleukin‐2 (IL‐2) cytokine family in
COVID‐19 pathogenesis and immunity. So we aimed to identify the potential in the role of …
COVID‐19 pathogenesis and immunity. So we aimed to identify the potential in the role of …
[HTML][HTML] Tailored immune responses: novel effector helper T cell subsets in protective immunity
Differentiation of naïve CD4+ cells into functionally distinct effector helper T cell subsets,
characterised by distinct “cytokine signatures,” is a cardinal strategy employed by the …
characterised by distinct “cytokine signatures,” is a cardinal strategy employed by the …
Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site
C Tan, MK Aziz, JD Lovaas, BP Vistica… - The Journal of …, 2010 - journals.aai.org
Recently reported lines of Th9 cells, producing IL-9 and IL-10, were generated by
polarization with IL-4 and TGF-β and activation with Abs against CD3 and CD28. In this …
polarization with IL-4 and TGF-β and activation with Abs against CD3 and CD28. In this …