[HTML][HTML] Novel biomarkers for the management of chronic hepatitis B
T Inoue, Y Tanaka - Clinical and molecular hepatology, 2020 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) cannot be eliminated completely from infected hepatocytes because
of the presence of intrahepatic covalently closed circular DNA (cccDNA). As chronic hepatitis …
of the presence of intrahepatic covalently closed circular DNA (cccDNA). As chronic hepatitis …
Updating the clinical application of blood biomarkers and their algorithms in the diagnosis and surveillance of hepatocellular carcinoma: a critical review
The most common primary liver cancer is hepatocellular carcinoma (HCC), and its mortality
rate is increasing globally. The overall 5-year survival of patients with liver cancer is …
rate is increasing globally. The overall 5-year survival of patients with liver cancer is …
Des-γ-carboxy prothrombin and α-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma
AS Lok, RK Sterling, JE Everhart, EC Wright, JC Hoefs… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: The outcome of patients with hepatocellular carcinoma (HCC)
remains poor because of late diagnosis. The aim of this study was to compare the accuracy …
remains poor because of late diagnosis. The aim of this study was to compare the accuracy …
The detection of hepatocellular carcinoma using a prospectively developed and validated model based on serological biomarkers
Background: Hepatocellular carcinoma is a common complication of chronic liver disease
(CLD), and is conventionally diagnosed by radiological means. We aimed to build a …
(CLD), and is conventionally diagnosed by radiological means. We aimed to build a …
Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats
Background Hepatology research has focused on developing traditional therapies as
pharmacological medicines to treat liver cirrhosis. Thus, this study evaluated mechanisms of …
pharmacological medicines to treat liver cirrhosis. Thus, this study evaluated mechanisms of …
[HTML][HTML] Glypican-3 is a prognostic factor and an immunotherapeutic target in hepatocellular carcinoma
Y Haruyama, H Kataoka - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
Abstract Glypican-3 (GPC3) is a cell surface oncofetal proteoglycan that is anchored by
glycosylphosphatidylinositol. Whereas GPC3 is abundant in fetal liver, its expression is …
glycosylphosphatidylinositol. Whereas GPC3 is abundant in fetal liver, its expression is …
Diagnostic performance of alpha-fetoprotein, protein induced by vitamin K absence, osteopontin, Dickkopf-1 and its combinations for hepatocellular carcinoma
ES Jang, SH Jeong, JW Kim, YS Choi, P Leissner… - PloS one, 2016 - journals.plos.org
Background & Aims Alpha-fetoprotein (AFP) is the most widely used serum biomarker for
hepatocellular carcinoma (HCC), despite its limitations. As complementary biomarkers …
hepatocellular carcinoma (HCC), despite its limitations. As complementary biomarkers …
Biomarkers: evaluation of screening for and early diagnosis of hepatocellular carcinoma in Japan and China
P Song, J Gao, Y Inagaki, N Kokudo, K Hasegawa… - Liver cancer, 2013 - karger.com
Over the past few decades, the screening for and early diagnosis of hepatocellular
carcinoma (HCC) has attracted attention worldwide, and especially in Asian countries such …
carcinoma (HCC) has attracted attention worldwide, and especially in Asian countries such …
[HTML][HTML] Oxidative stress and hepatocarcinogenesis
Y Fu, FL Chung - Hepatoma research, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths
worldwide. There are two major challenges for HCC, the first being that early detection is …
worldwide. There are two major challenges for HCC, the first being that early detection is …
Clinical and molecular insights into the hepatocellular carcinoma tumour marker des‐γ‐carboxyprothrombin
Y Inagaki, W Tang, M Makuuchi, K Hasegawa… - Liver …, 2011 - Wiley Online Library
Abstract Des‐γ‐carboxyprothrombin (DCP) is known as a tumour marker for hepatocellular
carcinoma (HCC). Various tumour markers have been developed for serological diagnosis …
carcinoma (HCC). Various tumour markers have been developed for serological diagnosis …